A peek inside the machines of bacterial nucleotide excision repair

• Main Authors: Thanyalak Kraithong, Silas Hartley, David Jeruzalmi, Danaya Pakotiprapha
• Other Authors: City College of New York
• Format: Review
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Chemical Engineering; Chemistry; Computer Science
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76309
• Institution: Mahidol University

Double stranded DNA (dsDNA), the repository of genetic information in bacteria, archaea and eukaryotes, exhibits a surprising instability in the intracellular environment; this fragility is exacerbated by exogenous agents, such as ultraviolet radiation. To protect themselves against the severe conse...