Within-host evolutionary dynamics of seasonal and pandemic human influenza a viruses in young children

• Main Authors: Alvin X. Han, Zandra C.Felix Garza, Matthijs R.A. Welkers, René M. Vigeveno, Tran Nhu Duong, Le Thi Quynh Mai, Pham Quang Thai, Dang Dinh Thoang, Tran Thi Ngoc Anh, Ha Manh Tuan, Nguyen Thanh Hung, Le Quoc Thinh, Le Thanh Hai, Hoang Thi Bich Ngoc, Kulkanya Chokephaibulkit, Pilaipan Puthavathana, Nguyen Van Vinh Chau, Nghiem My Ngoc, Nguyen Van Kinh, Dao Tuyet Trinh, Tran Tinh Hien, Heiman F.L. Wertheim, Peter Horby, Annette Fox, H. Rogier van Doorn, Dirk Eggink, Menno D. de Jong, Colin A. Russell
• Other Authors: Siriraj Hospital
• Format: Article
• Published: 2022
• Subjects: Biochemistry, Genetics and Molecular Biology; Immunology and Microbiology; Neuroscience
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76349
• Institution: Mahidol University

The evolution of influenza viruses is fundamentally shaped by within-host processes. However, the within-host evolutionary dynamics of influenza viruses remain incompletely understood, in part because most studies have focused on infections in healthy adults based on single timepoint data. Here, we...