Correction of Hemoglobin E/Beta-Thalassemia Patient-Derived iPSCs Using CRISPR/Cas9
HbE/β-thalassemia is one of the most common thalassemic syndromes in Southeast Asia and Thailand. Patients have mutations in β hemoglobin (HBB) gene resulting in decreased and/or abnormal production of β hemoglobin. Here, we describe a protocol for CRISPR/Cas9-mediated gene correction of the mutated...
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| Format: | Book Chapter |
| Published: |
2022
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/76423 |
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| Institution: | Mahidol University |