Recent advances in wide field and ultrawide field optical coherence tomography angiography in retinochoroidal pathologies

• Main Authors: Gagan Kalra, Francesco Pichi, Nitin Kumar Menia, Daraius Shroff, Nopasak Phasukkijwatana, Kanika Aggarwal, Aniruddha Agarwal
• Other Authors: Cleveland Clinic Abu Dhabi
• Format: Review
• Published: 2022
• Subjects: Engineering; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/76987
• Institution: Mahidol University

Introduction: With the advent of wide field (WF) and ultra-wide field (UWF) imaging in color fundus photography and fluorescein angiography (FA), the importance of an expanded field-of-view (FOV) has been illustrated for early detection of several chorioretinal disorders. The need to bring similar utility to optical coherence tomography angiography (OCTA) is imperative. Areas covered: For this review, we explored all research items with WF or UWF on Pubmed Central and Google Scholar. Software-based methods included algorithms for motion correction, artifact reduction, image pre-processing, post-processing and montage protocols while hardware methods included swept-source OCTA, faster scanning sources, hardware-based motion tracking and image registration, scanning sources with faster speeds and lower resolution. For various disorders such as diabetic retinopathy, uveitis, vascular disorders, among others, the increased FOV showed demonstrably increased detection rates and diagnostic yield. Expert opinion: Increased FOV in OCTA imaging is a meaningful and impactful step in ophthalmic imaging. Overcoming the hardware-based limitations can potentially yield higher FOV without loss of important details. In addition to improvements in the hardware and available equipment, better software tools and image processing algorithms may greatly enhance the utility of UWF OCTA in care of patients with various retinochoroidal diseases.