Leaky gut syndrome is associated with endotoxemia and serum (1→3)-β-d-glucan in severe dengue infection

• Main Authors: Wiwat Chancharoenthana, Asada Leelahavanichkul, Wassawon Ariyanon, Somratai Vadcharavivad, Suphasit Phatcharophaswattanakul, Supitcha Kamolratanakul, Pornsawan Leaungwutiwong, Weerapong Phumratanaprapin, Polrat Wilairatana
• Other Authors: Faculty of Tropical Medicine, Mahidol University
• Format: Article
• Published: 2022
• Subjects: Immunology and Microbiology; Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/77198
• Institution: Mahidol University

The hallmark of severe dengue infection is the increased vascular permeability and hemo-dynamic alteration that might be associated with an intestinal permeability defect. However, the mechanisms underlying the gastrointestinal-related symptoms of dengue are not well characterized. A prospective obs...