Evaluation of antigen-detecting and antibody-detecting diagnostic test combinations for diagnosing melioidosis

• Main Authors: Premjit Amornchai, Viriya Hantrakun, Gumphol Wongsuvan, Vanaporn Wuthiekanun, Surasakdi Wongratanacheewin, Prapit Teparrakkul, T. Eoin West, David P. Aucoin, Nicholas P.J. Day, Paul J. Brett, Mary N. Burtnick, Narisara Chantratitra, Direk Limmathurotsakul
• Other Authors: Faculty of Tropical Medicine, Mahidol University
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/77692
• Institution: Mahidol University

Background Melioidosis, an infectious disease caused by Burkholderia pseudomallei, is endemic in many tropical developing countries and has a high mortality. Here we evaluated combinations of a lateral flow immunoassay (LFI) detecting B. pseudomallei capsular polysaccharide (CPS) and enzyme-linked i...