X-treme loss of sequence diversity linked to neo-x chromosomes in filarial nematodes

• Main Authors: John Mattick, Silvia Libro, Robin Bromley, Wanpen Chaicumpa, Matthew Chung, Darren Cook, Mohammad Behram Khan, Nikhil Kumar, Yeeling Lau, Shailja Misra-Bhattacharya, Ramakrishna Rao, Lisa Sadzewicz, Atiporn Saeung, Mohd Shahab, Benjamin C. Sparklin, Andrew Steven, Joseph D. Turner, Luke J. Tallon, Mark J. Taylor, Andrew R. Moorhead, Michelle Michalski, Jeremy M. Foster, Julie C.Dunning Hotopp
• Other Authors: Siriraj Hospital
• Format: Article
• Published: 2022
• Subjects: Medicine
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/77783
• Institution: Mahidol University

The sequence diversity of natural and laboratory populations of Brugia pahangi and Brugia malayi was assessed with Illumina resequencing followed by mapping in order to identify single nucleotide variants and insertions/deletions. In natural and laboratory Brugia populations, there is a lack of sequ...