High Intrapatient Variability in Tacrolimus Exposure Calculated Over a Long Period Is Associated With De Novo Donor-Specific Antibody Development and/or Late Rejection in Thai Kidney Transplant Patients Receiving Concomitant CYP3A4/5 Inhibitors

High Intrapatient Variability in Tacrolimus Exposure Calculated Over a Long Period Is Associated With De Novo Donor-Specific Antibody Development and/or Late Rejection in Thai Kidney Transplant Patients Receiving Concomitant CYP3A4/5 Inhibitors

BACKGROUND: High intrapatient variability in tacrolimus trough levels (Tac IPV) is associated with poor allograft outcomes. Tac IPV was previously calculated using trough levels 6-12 months after kidney transplantation (KT). Data on the accuracy of Tac IPV calculation over a longer period, the assoc...

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Bibliographic Details
Main Authors: Nuttasith Larpparisuth, Tanapon Pongnatcha, Pera Panprom, Ratchawat Promraj, Nalinee Premasathian, Attapong Vongwiwatana
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
Subjects:
Medicine
Pharmacology, Toxicology and Pharmaceutics
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/77807
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Institution: Mahidol University

Internet

https://repository.li.mahidol.ac.th/handle/123456789/77807

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