Sesamin and sesamol attenuate H<inf>2</inf>O<inf>2</inf>-induced oxidative stress on human neuronal cells via the SIRT1-SIRT3-FOXO3a signaling pathway

Sesamin and sesamol attenuate H<inf>2</inf>O<inf>2</inf>-induced oxidative stress on human neuronal cells via the SIRT1-SIRT3-FOXO3a signaling pathway

Background: An imbalance of free radicals and antioxidant defense systems in physiological processes can result in protein/DNA damage, inflammation, and cellular apoptosis leading to neurodegenerative disorders such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and Huntington’s disease (HD)...

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Main Authors: Waralee Ruankham, Wilasinee Suwanjang, Prapimpun Wongchitrat, Virapong Prachayasittikul, Supaluk Prachayasittikul, Kamonrat Phopin
Other Authors: Mahidol University
Format: Article
Published: 2022
Subjects:
Medicine
Neuroscience
Nursing
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/78807
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Institution: Mahidol University

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https://repository.li.mahidol.ac.th/handle/123456789/78807

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