Identification of the metabolites of ivermectin in humans

Mass drug administration of ivermectin has been proposed as a possible malaria elimination tool. Ivermectin exhibits a mosquito-lethal effect well beyond its biological half-life, suggesting the presence of active slowly eliminated metabolites. Human liver microsomes, primary human hepatocytes, and...

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Bibliographic Details
Main Authors: Phornpimon Tipthara, Kevin C. Kobylinski, Markus Godejohann, Borimas Hanboonkunupakarn, Alison Roth, John H. Adams, Nicholas J. White, Podjanee Jittamala, Nicholas P.J. Day, Joel Tarning
Other Authors: Bruker BioSpin GmbH, Germany
Format: Article
Published: 2022
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/78903
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Institution: Mahidol University