A fungus-derived purpactin A as an inhibitor of TMEM16A chloride channels and mucin secretion in airway epithelial cells
TMEM16A is a Ca2+-activated Cl- channel involved in mucus secretion in inflamed airways and proposed as a drug target for diseases associated with mucus hypersecretion including asthma. This study aimed to identify novel inhibitors of TMEM16A-mediated Cl- secretion in airway epithelial cells from a...
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Main Authors: | Chantapol Yimnual, Saravut Satitsri, Baiq Nila Sari Ningsih, Vatcharin Rukachaisirikul, Chatchai Muanprasat |
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Other Authors: | Faculty of Medicine Ramathibodi Hospital, Mahidol University |
Format: | Article |
Published: |
2022
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Subjects: | |
Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/78954 |
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Institution: | Mahidol University |
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