Therapeutic opportunities for cancers presented by natural and synthetic compounds targeting the Hippo signaling pathway

A new trend in anti-cancer treatments through the disruption of the YAP-TEAD protein-protein interaction complex is recognized. YAP has been tipped as a key modulator of the Hippo signaling pathway. Binding of YAP to its transcription factor TEAD can lead to disease progression as it drives cell-pro...

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Bibliographic Details
Main Authors: Thanapon Charoenwongpaiboon, Chuti Laowtammathron, Chanchao Lorthongpanich
Other Authors: Siriraj Hospital
Format: Article
Published: 2022
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/79175
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Institution: Mahidol University