Etanercept prevents TNF-α mediated mandibular bone loss in FcγRIIb^-/- lupus model

• Main Authors: Nithidol Sakunrangsit, Piyanuch Metheepakornchai, Sarinya Kumpunya, Matthew Blake Greenblatt, Asada Leelahavanichkul, Prapaporn Pisitkun, Sutada Lotinun
• Other Authors: Ramathibodi Hospital
• Format: Article
• Published: 2022
• Subjects: Multidisciplinary
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/79364
• Institution: Mahidol University

Patients with systemic lupus erythematosus are at increased risk for alveolar bone loss due to periodontitis possibly as a result of a pathogenic immune response to oral bacteria and inflammation. The aim of the present study was to investigate whether an anti-TNF-α antagonist could prevent mandibul...