Outcome of Living Donor Hepatectomy for Pediatric Liver Transplantation: Report of 100 Cases at Ramathibodi Hospital

• Main Authors: Nuttapon Arpornsujaritkun, Surasak Leelaudomlipi, Abhasnee Sobhonslidsuk, Somkit Mingphruedhi, Sutipong Jongjirasiri, Pongphob Intaraprasong, Panuwat Lertsithichai, Bundit Sakulchairungreung, Goragoch Gesprasert, Veeravorn Ariyakhagorn, Suthus Sriphojanart, ณัฐพล อาภรณ์สุจริตกุล, สุรศักดิ์ ลีลาอุดมลิปิ, อาภัสณี โสภณสฤษฏ์สุข, สมคิด มิ่งพฤฒิ, สุทธิพงษ์ จงจิระศิริ, พงษ์ภพ อินทรประสงค์, ภาณุวัฒน์ เลิศสิทธิชัย, บัณฑิต สกุลชัยรุ่งเรือง, กรกช เกษประเสริฐ, วีระวร อริยขจร, สุทัศน์ ศรีพจนารถ
• Other Authors: Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of surgery
• Format: Original Article
• Language: English
• Published: 2022
• Subjects: living donor; การประมาณเวลาตาย; การเปลี่ยนแปลงภายหลังตาย; การชันสูตรพลิกศพ; การสอบสวนการตาย; liver donor; pediatric liver transplantation; complication
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/79611
• Institution: Mahidol University

Background: Liver transplantation (LT) is the standard treatment for end-stage liver disease, early-stage hepatocellular carcinoma and acute liver failure in adults and children. The shortage of donor organ is a barrier of decease donor LT, resulting in a high waiting-list mortality. Living donor liver transplantation (LDLT) has been performed in Thailand for 20 years to solve this problem. Objective: We evaluated the clinical outcomes after living donor hepatectomy. Methods: A retrospective study of living donor who underwent LDLT between 2001 and 2015 was performed. Clavien scoring system was used to grade the severity of complications. Result: One hundred living donors donated their parts of the livers, left lateral segment or left lobe, to their children. The operation was performed by one operative team. Complications did not occur in 91 donors. The common complications were wound problems (6%), bile leakage (2%) and bile duct injury (1%).Two donors required hospital readmission. Donor mortality is zero in 100 cases. Conclusions: Living donor hepatectomy for pediatric recipients was associated with a low complication rate in an experience team. Good operative planning may decrease the complication rate.