The Use of Quantitative Fluorescence PCR for Common Aneuploidy Detection in Prenatal Diagnosis

• Main Authors: Nittaya Rodratn, Jittima Shotivaranon, Takol Chareonsirisuthigul, Panyu Panburana, Budsaba Rerkamnuaychoke, นิตยา รอดรัตน์, จิตติมา โชติวรานนท์, ถกล เจริญศิริสุทธิกุล, พัญญู พันธ์บูรณะ, บุษบา ฤกษ์อำนวยโชค
• Other Authors: Mahidol University. Faculty of Medicine Ramathibodi Hospital. Department of Pathology
• Format: Original Article
• Language: English
• Published: 2022
• Subjects: Prenatal diagnosis; Aneuploidy; Rapid molecular technique; QF-PCR; STRs; การตรวจวินิจฉัยก่อนคลอด
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/79678
• Institution: Mahidol University

Background: The major type of chromosomal abnormality is aneuploidy which has the chance both too many and too few numbers of chromosomes. Trisomy is a common aneuploidy in prenatal diagnostic problem. The gold standard for detection of this abnormality is karyotype analysis. However, this method ha...