Selective α<inf>3</inf>β<inf>4</inf> Nicotinic Acetylcholine Receptor Ligand as a Potential Tracer for Drug Addiction
α3β4 Nicotinic acetylcholine receptor (nAChR) has been recognized as an emerging biomarker for the early detection of drug addiction. Herein, α3β4 nAChR ligands were designed and synthesized to improve the binding affinity and selectivity of two lead compounds, (S)-QND8 and (S)-T2, for the developme...
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Format: | Article |
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2023
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/81656 |
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Institution: | Mahidol University |