The standardized Centella asiatica extract ECa 233 regulates the catalytic activities of βAPP-cleaving secretases in human cell lines
Alzheimer’s disease is a neurodegenerative disorder characterized by the accumulation of amyloid peptides in the brain. While the production of Aβ is dependent on the cleavage of the β-amyloid precursor protein by the β-secretase BACE1, the α-secretase activity, mainly supported by ADAM10, counterba...
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| Format: | Article |
| Published: |
2023
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/82136 |
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| Institution: | Mahidol University |