Genetic Diversity of Taenia asiatica from Thailand and Other Geographical Locations as Revealed by Cytochrome c Oxidase Subunit 1 Sequences

• Main Authors: Malinee Thairungroj Anantaphruti, มาลินี ไทยรุ่งโรจน์ อนันต์พฤกษ์, Urusa Thaenkham, อุรุษา แทนขำ, Dorn Watthanakulpanich, ดร วัฒนกุลพานิชย์, Orawan Phuphisut, อรวรรณ พู่พิสุทธิ์, Wanna Maipanich, วรรณา ไมพานิช, Tippayarat Yoonuan, ทิพยรัตน์ อยู่นวล, Supaporn Nuamtanong, สุภาพร น่วมทะนง, Somjit Pubampen, สมจิตร ภู่บำเพ็ญ, Surapol Sanguankiat, สุรพล สงวนเกียรติ
• Format: Article
• Language: English
• Published: 2014
• Subjects: Cox1 gene,; Different geographical location; Genetic diversity; Taenia asiatica; Taenia saginata; Thailand; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/822
• Institution: Mahidol University

Twelve 924 bp cytochrome c oxidase subunit 1 (cox1) mitochondrial DNA sequences from Taenia asiatica isolates from Thailand were aligned and compared with multiple sequence isolates from Thailand and 6 other countries from the GenBank database. The genetic divergence of T. asiatica was also compared with Taenia saginata database sequences from 6 different countries in Asia, including Thailand, and 3 countries from other continents. The results showed that there were minor genetic variations within T. asiatica species, while high intraspecies variation was found in T. saginata. There were only 2 haplotypes and 1 polymorphic site found in T. asiatica, but 8 haplotypes and 9 polymorphic sites in T. saginata. Haplotype diversity was very low, 0.067, in T. asiatica and high, 0.700, in T. saginata. The very low genetic diversity suggested that T. asiatica may be at a risk due to the loss of potential adaptive alleles, resulting in reduced viability and decreased responses to environmental changes, which may endanger the species.