Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially...
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th-mahidol.829832023-06-10T00:04:33Z Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions Yuliwulandari R. Mahidol University Biochemistry, Genetics and Molecular Biology Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially in Asia, are yet to implement pre-emptive genetic screenings in clinical settings. Several studies have been published on the cost-effectiveness of genetics screening before treatment initiation. This chapter discusses the potential pharmacoeconomic implications of human leukocyte antigen (HLA) typing associated with some well-known and studied ADRs and the associated implementation into routine care. 2023-06-09T17:04:33Z 2023-06-09T17:04:33Z 2023-01-01 Book Chapter Economic Evaluation in Genomic and Precision Medicine (2023) , 71-86 10.1016/B978-0-12-813382-8.00003-3 2-s2.0-85160694959 https://repository.li.mahidol.ac.th/handle/123456789/82983 SCOPUS |
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Biochemistry, Genetics and Molecular Biology Yuliwulandari R. Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
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Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially in Asia, are yet to implement pre-emptive genetic screenings in clinical settings. Several studies have been published on the cost-effectiveness of genetics screening before treatment initiation. This chapter discusses the potential pharmacoeconomic implications of human leukocyte antigen (HLA) typing associated with some well-known and studied ADRs and the associated implementation into routine care. |
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Mahidol University |
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Mahidol University Yuliwulandari R. |
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Book Chapter |
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Yuliwulandari R. |
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Yuliwulandari R. |
title |
Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
title_short |
Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
title_full |
Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
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Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
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Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
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economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions |
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2023 |
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https://repository.li.mahidol.ac.th/handle/123456789/82983 |
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