Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions

Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially...

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Main Author: Yuliwulandari R.
Other Authors: Mahidol University
Format: Book Chapter
Published: 2023
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/82983
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Institution: Mahidol University
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spelling th-mahidol.829832023-06-10T00:04:33Z Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions Yuliwulandari R. Mahidol University Biochemistry, Genetics and Molecular Biology Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially in Asia, are yet to implement pre-emptive genetic screenings in clinical settings. Several studies have been published on the cost-effectiveness of genetics screening before treatment initiation. This chapter discusses the potential pharmacoeconomic implications of human leukocyte antigen (HLA) typing associated with some well-known and studied ADRs and the associated implementation into routine care. 2023-06-09T17:04:33Z 2023-06-09T17:04:33Z 2023-01-01 Book Chapter Economic Evaluation in Genomic and Precision Medicine (2023) , 71-86 10.1016/B978-0-12-813382-8.00003-3 2-s2.0-85160694959 https://repository.li.mahidol.ac.th/handle/123456789/82983 SCOPUS
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
spellingShingle Biochemistry, Genetics and Molecular Biology
Yuliwulandari R.
Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
description Adverse drug reactions (ADRs) can cause treatment interruptions as well as disability and sometimes death. Recent developments in genetics have shown that some ADRs could be avoided by using pharmacogenetic tests before treatment initiation. However, due to their novelty, many countries, especially in Asia, are yet to implement pre-emptive genetic screenings in clinical settings. Several studies have been published on the cost-effectiveness of genetics screening before treatment initiation. This chapter discusses the potential pharmacoeconomic implications of human leukocyte antigen (HLA) typing associated with some well-known and studied ADRs and the associated implementation into routine care.
author2 Mahidol University
author_facet Mahidol University
Yuliwulandari R.
format Book Chapter
author Yuliwulandari R.
author_sort Yuliwulandari R.
title Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
title_short Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
title_full Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
title_fullStr Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
title_full_unstemmed Economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
title_sort economic analysis of pharmacogenetics testing for human leukocyte antigen-based adverse drug reactions
publishDate 2023
url https://repository.li.mahidol.ac.th/handle/123456789/82983
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