Asymmetric synthesis of ent-anorisol A and its stereoisomers and confirmation of the absolute configuration of anorisol A isolated from Anogeissus rivularis

• Main Author: Chatpreecha R.
• Other Authors: Mahidol University
• Format: Article
• Published: 2023
• Subjects: Chemical Engineering
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/84119

Asymmetric synthesis of (2 S,3 S,4 R,5 S)-2-(2,4-dihydroxyphenyl)-5-(4-methoxyphenyl)-3,4-dimethyltetrahydrofuran named as ent-anorisol A was accomplished. The uncommon relative 2,3-anti-3,4-syn-4,5-syn stereochemistry across tetrahydrofuran (THF) ring of ent-anorisol A was constructed with high yie...