Molecular insights into the adsorption mechanism of E21R and T7E21R human defensin 5 on a bacterial membrane
Human defensin 5 (HD5) is an antimicrobial peptide (AMP) with a broad-spectrum antimicrobial activity. Hence, it serves as a good candidate in AMP-derived antibiotic design. A substitution of E21 with arginine (E21R) and a second replacement of T7 with arginine (T7E21R) were found to enhance the ant...
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| Format: | Article |
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2023
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| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/84122 |
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| Institution: | Mahidol University |