Simultaneous and enantiospecific quantification of primaquine and carboxyprimaquine in human plasma using liquid chromatography-tandem mass spectrometry
Background: The enantiomers of the 8-aminoquinoline anti-malarial primaquine have different pharmacological properties. Development of an analytical method for simultaneous quantification of the enantiomers of primaquine and its metabolite, carboxyprimaquine, will support clinical pharmacometric ass...
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Format: | Article |
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2023
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/84858 |
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Institution: | Mahidol University |