Monkeypox: A Comprehensive Review
The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The eti...
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th-mahidol.848922023-06-19T00:21:48Z Monkeypox: A Comprehensive Review Harapan H. Mahidol University Immunology and Microbiology The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers, public health policymakers, and the general public worldwide need to be well-informed on this relatively neglected viral disease. Here, we provide a comprehensive and up-to-date overview of monkeypox, including the following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, and management. In addition, the current review discusses the preventive and control measures, the latest vaccine developments, and the future research areas in this re-emerging viral disease that was declared as a public health emergency of international concern. 2023-06-18T17:21:48Z 2023-06-18T17:21:48Z 2022-10-01 Review Viruses Vol.14 No.10 (2022) 10.3390/v14102155 19994915 36298710 2-s2.0-85140634842 https://repository.li.mahidol.ac.th/handle/123456789/84892 SCOPUS |
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Immunology and Microbiology Harapan H. Monkeypox: A Comprehensive Review |
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The 2022 multi-country monkeypox outbreak in humans has brought new public health adversity on top of the ongoing coronavirus disease 2019 (COVID-19) pandemic. The disease has spread to 104 countries throughout six continents of the world, with the highest burden in North America and Europe. The etiologic agent, monkeypox virus (MPXV), has been known since 1959 after isolation from infected monkeys, and virulence among humans has been reported since the 1970s, mainly in endemic countries in West and Central Africa. However, the disease has re-emerged in 2022 at an unprecedented pace, with particular concern on its human-to-human transmissibility and community spread in non-endemic regions. As a mitigation effort, healthcare workers, public health policymakers, and the general public worldwide need to be well-informed on this relatively neglected viral disease. Here, we provide a comprehensive and up-to-date overview of monkeypox, including the following aspects: epidemiology, etiology, pathogenesis, clinical features, diagnosis, and management. In addition, the current review discusses the preventive and control measures, the latest vaccine developments, and the future research areas in this re-emerging viral disease that was declared as a public health emergency of international concern. |
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Mahidol University |
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Mahidol University Harapan H. |
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Review |
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Harapan H. |
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Harapan H. |
title |
Monkeypox: A Comprehensive Review |
title_short |
Monkeypox: A Comprehensive Review |
title_full |
Monkeypox: A Comprehensive Review |
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Monkeypox: A Comprehensive Review |
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Monkeypox: A Comprehensive Review |
title_sort |
monkeypox: a comprehensive review |
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2023 |
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https://repository.li.mahidol.ac.th/handle/123456789/84892 |
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1781416231461453824 |