Diagnosis and classification of optic neuritis

There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can...

Full description

Saved in:
Bibliographic Details
Main Author: Petzold A.
Other Authors: Mahidol University
Format: Review
Published: 2023
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/85231
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University
id th-mahidol.85231
record_format dspace
spelling th-mahidol.852312023-06-19T00:37:45Z Diagnosis and classification of optic neuritis Petzold A. Mahidol University Medicine There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups. 2023-06-18T17:37:45Z 2023-06-18T17:37:45Z 2022-12-01 Review The Lancet Neurology Vol.21 No.12 (2022) , 1120-1134 10.1016/S1474-4422(22)00200-9 14744465 14744422 36179757 2-s2.0-85141992725 https://repository.li.mahidol.ac.th/handle/123456789/85231 SCOPUS
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Petzold A.
Diagnosis and classification of optic neuritis
description There is no consensus regarding the classification of optic neuritis, and precise diagnostic criteria are not available. This reality means that the diagnosis of disorders that have optic neuritis as the first manifestation can be challenging. Accurate diagnosis of optic neuritis at presentation can facilitate the timely treatment of individuals with multiple sclerosis, neuromyelitis optica spectrum disorder, or myelin oligodendrocyte glycoprotein antibody-associated disease. Epidemiological data show that, cumulatively, optic neuritis is most frequently caused by many conditions other than multiple sclerosis. Worldwide, the cause and management of optic neuritis varies with geographical location, treatment availability, and ethnic background. We have developed diagnostic criteria for optic neuritis and a classification of optic neuritis subgroups. Our diagnostic criteria are based on clinical features that permit a diagnosis of possible optic neuritis; further paraclinical tests, utilising brain, orbital, and retinal imaging, together with antibody and other protein biomarker data, can lead to a diagnosis of definite optic neuritis. Paraclinical tests can also be applied retrospectively on stored samples and historical brain or retinal scans, which will be useful for future validation studies. Our criteria have the potential to reduce the risk of misdiagnosis, provide information on optic neuritis disease course that can guide future treatment trial design, and enable physicians to judge the likelihood of a need for long-term pharmacological management, which might differ according to optic neuritis subgroups.
author2 Mahidol University
author_facet Mahidol University
Petzold A.
format Review
author Petzold A.
author_sort Petzold A.
title Diagnosis and classification of optic neuritis
title_short Diagnosis and classification of optic neuritis
title_full Diagnosis and classification of optic neuritis
title_fullStr Diagnosis and classification of optic neuritis
title_full_unstemmed Diagnosis and classification of optic neuritis
title_sort diagnosis and classification of optic neuritis
publishDate 2023
url https://repository.li.mahidol.ac.th/handle/123456789/85231
_version_ 1781415661794230272