Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause

Objective: Initiation of and compliance with menopausal hormonal therapy (MHT) have been dropping due to the 2002 Women’s Health Initiative (WHI) publication. We evaluated the change in practice of MHT for surgical menopause after implementing the 2013 ‘Global Consensus Statement on MHT’ to our inst...

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Main Author: Techatraisak K.
Other Authors: Mahidol University
Format: Article
Published: 2023
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/86737
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spelling th-mahidol.867372023-06-19T01:08:32Z Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause Techatraisak K. Mahidol University Medicine Objective: Initiation of and compliance with menopausal hormonal therapy (MHT) have been dropping due to the 2002 Women’s Health Initiative (WHI) publication. We evaluated the change in practice of MHT for surgical menopause after implementing the 2013 ‘Global Consensus Statement on MHT’ to our institutional guideline. Methods: A retrospective study was conducted in surgically menopausal women newly registering at the Siriraj Menopause Clinic in a university hospital, Thailand, from 1995 to 2013. The patients were categorized into four groups according to periods of MHT initiation: 1995–1998 (control), 2000–2003 (WHI affected), 2005–2008 (post WHI) and 2010–2013 (Global Consensus Statement affected). Their 3-year compliance with MHT was compared using forward stepwise regression analysis. Results: There were 288, 156, 107 and 104 cases in the 1995–1998, 2000–2003, 2005–2008 and 2010–2013 groups. Their mean age at surgery was 42.8 ± 4.7 years. After the first, second and third years, overall compliance was 82.4%, 70.9% and 61.2%, respectively. The 3-year compliance drastically dropped in the 2000–2003 group, and then improved to control level in the 2010–2013 group (51.9% vs. 77.9%, p = 0.035). Conclusion: The initiation of MHT continuously dropped during 2000–2013; however, compliance with MHT initiated during 2010–2013 improved after implementing the 2013 ‘Global Consensus Statement on MHT’ to our institutional guideline. Each institute should have a strategy to encourage the initiation of and compliance with MHT for surgical menopause to achieve long-term health benefits. 2023-06-18T18:08:32Z 2023-06-18T18:08:32Z 2022-01-01 Article Climacteric Vol.25 No.3 (2022) , 300-305 10.1080/13697137.2021.1978424 14730804 13697137 34726130 2-s2.0-85118530123 https://repository.li.mahidol.ac.th/handle/123456789/86737 SCOPUS
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Techatraisak K.
Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
description Objective: Initiation of and compliance with menopausal hormonal therapy (MHT) have been dropping due to the 2002 Women’s Health Initiative (WHI) publication. We evaluated the change in practice of MHT for surgical menopause after implementing the 2013 ‘Global Consensus Statement on MHT’ to our institutional guideline. Methods: A retrospective study was conducted in surgically menopausal women newly registering at the Siriraj Menopause Clinic in a university hospital, Thailand, from 1995 to 2013. The patients were categorized into four groups according to periods of MHT initiation: 1995–1998 (control), 2000–2003 (WHI affected), 2005–2008 (post WHI) and 2010–2013 (Global Consensus Statement affected). Their 3-year compliance with MHT was compared using forward stepwise regression analysis. Results: There were 288, 156, 107 and 104 cases in the 1995–1998, 2000–2003, 2005–2008 and 2010–2013 groups. Their mean age at surgery was 42.8 ± 4.7 years. After the first, second and third years, overall compliance was 82.4%, 70.9% and 61.2%, respectively. The 3-year compliance drastically dropped in the 2000–2003 group, and then improved to control level in the 2010–2013 group (51.9% vs. 77.9%, p = 0.035). Conclusion: The initiation of MHT continuously dropped during 2000–2013; however, compliance with MHT initiated during 2010–2013 improved after implementing the 2013 ‘Global Consensus Statement on MHT’ to our institutional guideline. Each institute should have a strategy to encourage the initiation of and compliance with MHT for surgical menopause to achieve long-term health benefits.
author2 Mahidol University
author_facet Mahidol University
Techatraisak K.
format Article
author Techatraisak K.
author_sort Techatraisak K.
title Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
title_short Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
title_full Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
title_fullStr Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
title_full_unstemmed Impact of Global Consensus Statement on compliance with hormonal therapy for surgical menopause
title_sort impact of global consensus statement on compliance with hormonal therapy for surgical menopause
publishDate 2023
url https://repository.li.mahidol.ac.th/handle/123456789/86737
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