Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children

Even though tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is usually found in HIV-positive patients receiving antiviral treatment, it can also occur in HIV-negative patients especially if they have risk factors. We report a unique case of TB-IRIS in an immunocompetent child pres...

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Main Author: Palamit A.
Other Authors: Mahidol University
Format: Article
Published: 2023
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/87319
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spelling th-mahidol.873192023-06-20T12:31:40Z Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children Palamit A. Mahidol University Medicine Even though tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is usually found in HIV-positive patients receiving antiviral treatment, it can also occur in HIV-negative patients especially if they have risk factors. We report a unique case of TB-IRIS in an immunocompetent child presenting with new onset of pleuritic chest pain after receiving anti-TB drugs. TB-IRIS should be considered as a differential diagnosis in case of clinical deterioration or appearance of new typical lesions despite appropriate anti-TB treatment for more than 2 weeks in the absence of persistently active TB or any other alternative causes. This will prevent physicians from misdiagnosis as superimposed infections, treatment failure or TB relapse. 2023-06-20T05:31:40Z 2023-06-20T05:31:40Z 2022-05-01 Article Respirology Case Reports Vol.10 No.5 (2022) 10.1002/rcr2.945 20513380 2-s2.0-85128864062 https://repository.li.mahidol.ac.th/handle/123456789/87319 SCOPUS
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
Palamit A.
Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
description Even though tuberculosis-immune reconstitution inflammatory syndrome (TB-IRIS) is usually found in HIV-positive patients receiving antiviral treatment, it can also occur in HIV-negative patients especially if they have risk factors. We report a unique case of TB-IRIS in an immunocompetent child presenting with new onset of pleuritic chest pain after receiving anti-TB drugs. TB-IRIS should be considered as a differential diagnosis in case of clinical deterioration or appearance of new typical lesions despite appropriate anti-TB treatment for more than 2 weeks in the absence of persistently active TB or any other alternative causes. This will prevent physicians from misdiagnosis as superimposed infections, treatment failure or TB relapse.
author2 Mahidol University
author_facet Mahidol University
Palamit A.
format Article
author Palamit A.
author_sort Palamit A.
title Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
title_short Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
title_full Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
title_fullStr Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
title_full_unstemmed Tuberculosis-immune reconstitution inflammatory syndrome in HIV-negative children
title_sort tuberculosis-immune reconstitution inflammatory syndrome in hiv-negative children
publishDate 2023
url https://repository.li.mahidol.ac.th/handle/123456789/87319
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