Indoxyl sulfate impairs in vitro erythropoiesis by triggering apoptosis and senescence

Anemia is a major complication in over 50% of chronic kidney disease (CKD) patients. One of the main causes of anemia in CKD is the reduction of erythropoietin (EPO) synthesis from renal tubular cells. Therefore, first-line treatment of CKD is EPO administration; however, EPO unresponsiveness in sev...

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Bibliographic Details
Main Author: Duangchan T.
Other Authors: Mahidol University
Format: Article
Published: 2023
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/87489
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Institution: Mahidol University