Cyclooxygenase-2 inhibitory activity and antimalarial activity of chromone derivatives
A series of chromone derivatives were evaluated as cyclooxygenase 2 (COX-2) inhibitors and antimalarial agents. For COX-2 inhibition, the ten most potent compounds (25, 29, 31, 34, 35, 38,39, 41, 48 and 49) and celecoxib were further determined for the selectivity index (SI). Compounds 35 and 38 sho...
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Language: | English |
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Mahidol University. Mahidol University Library and Knowledge Center
2023
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Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/89826 |
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Institution: | Mahidol University |
Language: | English |