Permeability changes of integrin-containing multivesicular structures triggered by picornavirus entry.

• Main Authors: Pan Soonsawad, แพน สุ่นสวัสดิ์, Wattana Weerachatyanukul, วัฒนา วีรชาติยานุกูล, Paavolainen, Lassi, Upla, Paula, Rintanen, Nina, Espinoza, Juan, McNerney, Gregory, Marjomäki, Varpu, Cheng, R. Holland
• Other Authors: Mahidol University. Faculty of Dentistry. Department of Anatomy
• Format: Article
• Language: English
• Published: 2015
• Subjects: Cell membranes; Permeability; Endosomes; Antibodies; Integrins; Membrane structures; Vesicles; Virus uncoating; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/937
• Institution: Mahidol University

Cellular uptake of clustered α2β1-integrin induces the formation of membrane compartments that subsequently mature into a multivesicular body (MVB). Enhanced internalization mediated by clustered integrins was observed upon infection by the picornavirus echovirus 1 (EVI). We elucidated the structura...