Overexpression of receptor for advanced glycation end products and high-mobility group box 1 in human dental pulp inflammation.

• Main Authors: Salunya Tancharoen, ศรัณยา ตันเจริญ, Tassanee Tengrungsun, ทัศนีย์ เต็งรังสรรค์, Theeralaksna Suddhasthira, ธีรลักษณ์ สุทธเสถียร, Kikuchi, Kiyoshi, Vechvongvan, Nuttavun, Tokuda, Masayuki, Maruyama, Ikuro
• Other Authors: Mahidol University. Faculty of Dentistry. Department of Pharmacology
• Format: Article
• Language: English
• Published: 2015
• Subjects: HMGB1 protein; Dental pulp; In vitro techniques; Immunologic; Open Access article
• Online Access: https://repository.li.mahidol.ac.th/handle/123456789/942
• Institution: Mahidol University

High mobility group box 1 (HMGB1), a nonhistone DNA-binding protein, is released into the extracellular space and promotes inflammation. HMGB1 binds to related cell signaling transduction receptors, including receptor for advanced glycation end products (RAGE), which actively participate in vascular...