Antiinflammatory activity of flavonoids
Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyra...
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th-mahidol.95402018-02-27T11:30:08Z Antiinflammatory activity of flavonoids A. Panthong D. Kanjanapothi P. Tuntiwachwuttikul O. Pancharoen V. Reutrakul Chiang Mai University Silpakorn University Thailand Ministry of Public Health Mahidol University Biochemistry, Genetics and Molecular Biology Medicine Pharmacology, Toxicology and Pharmaceutics Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyrano ring B of the flavonoid molecule. Negligible or low antiinflammatory activities were found in the chalcone derivatives. The difference in the efficacy of the flavonoids tested possibly depends on their pharmacokinetic properties. © 1994, Gustav Fischer Verlag, Stuttgart · Jena · New York. All rights reserved. 2018-02-27T04:25:45Z 2018-02-27T04:25:45Z 1994-01-01 Article Phytomedicine. Vol.1, No.2 (1994), 141-144 10.1016/S0944-7113(11)80032-2 09447113 2-s2.0-85016784652 https://repository.li.mahidol.ac.th/handle/123456789/9540 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85016784652&origin=inward |
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Biochemistry, Genetics and Molecular Biology Medicine Pharmacology, Toxicology and Pharmaceutics |
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Biochemistry, Genetics and Molecular Biology Medicine Pharmacology, Toxicology and Pharmaceutics A. Panthong D. Kanjanapothi P. Tuntiwachwuttikul O. Pancharoen V. Reutrakul Antiinflammatory activity of flavonoids |
| description |
Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyrano ring B of the flavonoid molecule. Negligible or low antiinflammatory activities were found in the chalcone derivatives. The difference in the efficacy of the flavonoids tested possibly depends on their pharmacokinetic properties. © 1994, Gustav Fischer Verlag, Stuttgart · Jena · New York. All rights reserved. |
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Chiang Mai University |
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Chiang Mai University A. Panthong D. Kanjanapothi P. Tuntiwachwuttikul O. Pancharoen V. Reutrakul |
| format |
Article |
| author |
A. Panthong D. Kanjanapothi P. Tuntiwachwuttikul O. Pancharoen V. Reutrakul |
| author_sort |
A. Panthong |
| title |
Antiinflammatory activity of flavonoids |
| title_short |
Antiinflammatory activity of flavonoids |
| title_full |
Antiinflammatory activity of flavonoids |
| title_fullStr |
Antiinflammatory activity of flavonoids |
| title_full_unstemmed |
Antiinflammatory activity of flavonoids |
| title_sort |
antiinflammatory activity of flavonoids |
| publishDate |
2018 |
| url |
https://repository.li.mahidol.ac.th/handle/123456789/9540 |
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1763487760045309952 |