Antiinflammatory activity of flavonoids

Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyra...

Full description

Saved in:
Bibliographic Details
Main Authors: A. Panthong, D. Kanjanapothi, P. Tuntiwachwuttikul, O. Pancharoen, V. Reutrakul
Other Authors: Chiang Mai University
Format: Article
Published: 2018
Subjects:
Online Access:https://repository.li.mahidol.ac.th/handle/123456789/9540
Tags: Add Tag
No Tags, Be the first to tag this record!
Institution: Mahidol University
id th-mahidol.9540
record_format dspace
spelling th-mahidol.95402018-02-27T11:30:08Z Antiinflammatory activity of flavonoids A. Panthong D. Kanjanapothi P. Tuntiwachwuttikul O. Pancharoen V. Reutrakul Chiang Mai University Silpakorn University Thailand Ministry of Public Health Mahidol University Biochemistry, Genetics and Molecular Biology Medicine Pharmacology, Toxicology and Pharmaceutics Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyrano ring B of the flavonoid molecule. Negligible or low antiinflammatory activities were found in the chalcone derivatives. The difference in the efficacy of the flavonoids tested possibly depends on their pharmacokinetic properties. © 1994, Gustav Fischer Verlag, Stuttgart · Jena · New York. All rights reserved. 2018-02-27T04:25:45Z 2018-02-27T04:25:45Z 1994-01-01 Article Phytomedicine. Vol.1, No.2 (1994), 141-144 10.1016/S0944-7113(11)80032-2 09447113 2-s2.0-85016784652 https://repository.li.mahidol.ac.th/handle/123456789/9540 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85016784652&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Biochemistry, Genetics and Molecular Biology
Medicine
Pharmacology, Toxicology and Pharmaceutics
spellingShingle Biochemistry, Genetics and Molecular Biology
Medicine
Pharmacology, Toxicology and Pharmaceutics
A. Panthong
D. Kanjanapothi
P. Tuntiwachwuttikul
O. Pancharoen
V. Reutrakul
Antiinflammatory activity of flavonoids
description Fourteen flavonoids (flavones,- flavanones and chalcones) were assayed for oral antiinflammatory activity using carrageenan-induced hind paw edema in rats. The structural features necessary for antiinflammatory activity appear to be the presence of methoxyl groups at C5 and C7 of ring A and the pyrano ring B of the flavonoid molecule. Negligible or low antiinflammatory activities were found in the chalcone derivatives. The difference in the efficacy of the flavonoids tested possibly depends on their pharmacokinetic properties. © 1994, Gustav Fischer Verlag, Stuttgart · Jena · New York. All rights reserved.
author2 Chiang Mai University
author_facet Chiang Mai University
A. Panthong
D. Kanjanapothi
P. Tuntiwachwuttikul
O. Pancharoen
V. Reutrakul
format Article
author A. Panthong
D. Kanjanapothi
P. Tuntiwachwuttikul
O. Pancharoen
V. Reutrakul
author_sort A. Panthong
title Antiinflammatory activity of flavonoids
title_short Antiinflammatory activity of flavonoids
title_full Antiinflammatory activity of flavonoids
title_fullStr Antiinflammatory activity of flavonoids
title_full_unstemmed Antiinflammatory activity of flavonoids
title_sort antiinflammatory activity of flavonoids
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/9540
_version_ 1763487760045309952