Resistance to artemisinin of malaria parasites (Plasmodium falciparum) infecting α-thalassemic erythrocytes in vitro. Competition in drug accumulation with uninfected erythrocytes
Plasmodium falciparum infecting hemoglobin (Hb)H and/or Hb Constant Spring erythrocytes has higher resistance to artemisinin in vitro than when infecting normal erythrocytes. This is due to low drug accumulation of infected erythrocytes resulting from competition with uninfected variant erythrocytes...
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| Main Authors: | , , , |
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| Other Authors: | |
| Format: | Article |
| Published: |
2018
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| Subjects: | |
| Online Access: | https://repository.li.mahidol.ac.th/handle/123456789/9728 |
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| Institution: | Mahidol University |