Human pythiosis in Thailand

Pythium insidiosum is a protoctista and causes diseases in plants and animals. In Thailand it can cause a unique human infection of three types. The first type is a subcutaneous lesion in thalassaemic patients, with the pathological findings of a granulomatous reaction, diffuse infiltration, and oed...

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Main Author: P. Imwidthaya
Other Authors: Mahidol University
Format: Review
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/9767
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spelling th-mahidol.97672018-02-27T11:28:40Z Human pythiosis in Thailand P. Imwidthaya Mahidol University Medicine Pythium insidiosum is a protoctista and causes diseases in plants and animals. In Thailand it can cause a unique human infection of three types. The first type is a subcutaneous lesion in thalassaemic patients, with the pathological findings of a granulomatous reaction, diffuse infiltration, and oedema of the vessel walls. The patients responded to a saturated solution of potassium iodide. The second type is chronic inflammation and occlusion of blood vessels mainly in the lower extremities which results in gangrene or aneurysm formation. This type of infection is only found in thalassaemic patients and leads to amputation of the affected extremities or resection of the involved arteries. The third type is keratitis. This type of infection may or may not be associated with thalassaemia. The clinical signs and symptoms do not differentiate it from other types of myocotic keratitis. The patients end up with keratoplasty, evisceration or enucleation. Thailand is an agricultural country, and there are plenty of swampy areas and several plants to support the life cycle of Pythium. Moreover, many people suffer from thalassaemia, and there is no drug available for Pythium. Pythiosis plays an important role in medicine in Thailand. 2018-02-27T04:28:40Z 2018-02-27T04:28:40Z 1994-01-01 Review Postgraduate Medical Journal. Vol.70, No.826 (1994), 558-560 10.1136/pgmj.70.826.558 00325473 2-s2.0-0028142203 https://repository.li.mahidol.ac.th/handle/123456789/9767 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0028142203&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Medicine
spellingShingle Medicine
P. Imwidthaya
Human pythiosis in Thailand
description Pythium insidiosum is a protoctista and causes diseases in plants and animals. In Thailand it can cause a unique human infection of three types. The first type is a subcutaneous lesion in thalassaemic patients, with the pathological findings of a granulomatous reaction, diffuse infiltration, and oedema of the vessel walls. The patients responded to a saturated solution of potassium iodide. The second type is chronic inflammation and occlusion of blood vessels mainly in the lower extremities which results in gangrene or aneurysm formation. This type of infection is only found in thalassaemic patients and leads to amputation of the affected extremities or resection of the involved arteries. The third type is keratitis. This type of infection may or may not be associated with thalassaemia. The clinical signs and symptoms do not differentiate it from other types of myocotic keratitis. The patients end up with keratoplasty, evisceration or enucleation. Thailand is an agricultural country, and there are plenty of swampy areas and several plants to support the life cycle of Pythium. Moreover, many people suffer from thalassaemia, and there is no drug available for Pythium. Pythiosis plays an important role in medicine in Thailand.
author2 Mahidol University
author_facet Mahidol University
P. Imwidthaya
format Review
author P. Imwidthaya
author_sort P. Imwidthaya
title Human pythiosis in Thailand
title_short Human pythiosis in Thailand
title_full Human pythiosis in Thailand
title_fullStr Human pythiosis in Thailand
title_full_unstemmed Human pythiosis in Thailand
title_sort human pythiosis in thailand
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/9767
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