Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro

Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (a...

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Main Authors: T. Glinsukon, S. Sinlapanapaporn, M. Chulasamaya
Other Authors: Mahidol University
Format: Article
Published: 2018
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Online Access:https://repository.li.mahidol.ac.th/handle/123456789/9871
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spelling th-mahidol.98712018-02-27T11:30:09Z Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro T. Glinsukon S. Sinlapanapaporn M. Chulasamaya Mahidol University Pharmacology, Toxicology and Pharmaceutics Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (approx. 16.7%) by Cyto. E at a concentration as low as 1.0 μg/ml within 30 min. This inhibitory effect of Cyto. E was a dose-dependent at the concentrations ranging from 1.0-20.0 μg/ml. These findings demonstrate that cytochalasins are powerful inhibitors on the motility of rat epididymal spermatozoa. 2018-02-27T04:30:09Z 2018-02-27T04:30:09Z 1986-01-01 Article Research Communications in Chemical Pathology and Pharmacology. Vol.51, No.2 (1986), 265-268 00345164 2-s2.0-0022649384 https://repository.li.mahidol.ac.th/handle/123456789/9871 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022649384&origin=inward
institution Mahidol University
building Mahidol University Library
continent Asia
country Thailand
Thailand
content_provider Mahidol University Library
collection Mahidol University Institutional Repository
topic Pharmacology, Toxicology and Pharmaceutics
spellingShingle Pharmacology, Toxicology and Pharmaceutics
T. Glinsukon
S. Sinlapanapaporn
M. Chulasamaya
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
description Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (approx. 16.7%) by Cyto. E at a concentration as low as 1.0 μg/ml within 30 min. This inhibitory effect of Cyto. E was a dose-dependent at the concentrations ranging from 1.0-20.0 μg/ml. These findings demonstrate that cytochalasins are powerful inhibitors on the motility of rat epididymal spermatozoa.
author2 Mahidol University
author_facet Mahidol University
T. Glinsukon
S. Sinlapanapaporn
M. Chulasamaya
format Article
author T. Glinsukon
S. Sinlapanapaporn
M. Chulasamaya
author_sort T. Glinsukon
title Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
title_short Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
title_full Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
title_fullStr Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
title_full_unstemmed Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
title_sort inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
publishDate 2018
url https://repository.li.mahidol.ac.th/handle/123456789/9871
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