Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro
Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (a...
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th-mahidol.98712018-02-27T11:30:09Z Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro T. Glinsukon S. Sinlapanapaporn M. Chulasamaya Mahidol University Pharmacology, Toxicology and Pharmaceutics Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (approx. 16.7%) by Cyto. E at a concentration as low as 1.0 μg/ml within 30 min. This inhibitory effect of Cyto. E was a dose-dependent at the concentrations ranging from 1.0-20.0 μg/ml. These findings demonstrate that cytochalasins are powerful inhibitors on the motility of rat epididymal spermatozoa. 2018-02-27T04:30:09Z 2018-02-27T04:30:09Z 1986-01-01 Article Research Communications in Chemical Pathology and Pharmacology. Vol.51, No.2 (1986), 265-268 00345164 2-s2.0-0022649384 https://repository.li.mahidol.ac.th/handle/123456789/9871 Mahidol University SCOPUS https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=0022649384&origin=inward |
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Pharmacology, Toxicology and Pharmaceutics T. Glinsukon S. Sinlapanapaporn M. Chulasamaya Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
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Cytochalasins, A, B, C, D and E at a concentration of 5.0 μg/ml significantly inhibited the motility of spermatozoa collected from the cauda epididymidis of rats when diluted in Hank's solution containing BSA by 21.6-38.1% within a few min incubation. The motility was significantly inhibited (approx. 16.7%) by Cyto. E at a concentration as low as 1.0 μg/ml within 30 min. This inhibitory effect of Cyto. E was a dose-dependent at the concentrations ranging from 1.0-20.0 μg/ml. These findings demonstrate that cytochalasins are powerful inhibitors on the motility of rat epididymal spermatozoa. |
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Mahidol University |
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Mahidol University T. Glinsukon S. Sinlapanapaporn M. Chulasamaya |
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T. Glinsukon S. Sinlapanapaporn M. Chulasamaya |
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T. Glinsukon |
title |
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
title_short |
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
title_full |
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
title_fullStr |
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
title_full_unstemmed |
Inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
title_sort |
inhibitory effect of cytochalasins on the motility of rat epididymal spermatozoa in vitro |
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2018 |
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https://repository.li.mahidol.ac.th/handle/123456789/9871 |
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1763489959302397952 |