Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity
Thesis (M.Sc., Applied Chemistry)--Prince of Songkla University, 2020
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Prince of Songkla University
2023
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| Online Access: | http://kb.psu.ac.th/psukb/handle/2016/19120 |
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th-psu.2016-191202023-12-04T03:12:35Z Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity Selly Arvinda Rakhman Weeraya Khummueng Faculty of Science (Chemistry) คณะวิทยาศาสตร์ ภาควิชาเคมี Extraction (Chemistry) Thesis (M.Sc., Applied Chemistry)--Prince of Songkla University, 2020 Green synthesis is one of method for synthesize nanoparticles using biological material. Metal nanoparticles in this research will be produced by synthesis of M. elengi leaf extract that combine with metal precursor to make silver nanoparticle (AgNP) and zinc oxide nanoparticle (ZnONP). Characterization of metal nanoparticle used FTIR, UV-Visible spectrophotometer, XRD and TEM. Application of metal nanoparticle were antioxidant and cytotoxicity against colon cancer, Caco-2. Silver nanoparticles (AgNP) revealed that it has mostly round shapes with the particle size of AgNP was 16.84 nm - 33.67 nm or the average of particle size was 22.12 nm. Zinc Oxide Nanoparticles (ZnONP) characterization revealed that it has mostly round shapes with the particle size was 18.56 - 40.04 nm or the particle size was 28.44 nm in average. Application as antioxidant based on ECso value for extract, AgNP and ZnONP by DPPH assay get the result 139.97 mg/L, 237.33 mg/L and 5380.20 mg/L. The other method by ABTS assay have the result 37.34 mg/L, 215.45 mg/L and 2785.41 mg/L. The last method for FRAP assay showed the value 4.03 μM FE/ mM extract, 0.97 μM FE/ mg extract and 0.09 μM FE/ mg extract. Cytotoxicity of extract and nanoparticles (AgNP and ZnONP) showed that only extract at 2000 ppm has potential against colon cancer (Caco-2 cell) but no effect of nanoparticles (AgNP and ZnONP). 2023-12-04T03:08:28Z 2023-12-04T03:08:28Z 2020 Thesis http://kb.psu.ac.th/psukb/handle/2016/19120 en Attribution-NonCommercial-NoDerivs 3.0 Thailand http://creativecommons.org/licenses/by-nc-nd/3.0/th/ application/pdf Prince of Songkla University |
| institution |
Prince of Songkhla University |
| building |
Khunying Long Athakravi Sunthorn Learning Resources Center |
| continent |
Asia |
| country |
Thailand Thailand |
| content_provider |
Khunying Long Athakravi Sunthorn Learning Resources Center |
| collection |
PSU Knowledge Bank |
| language |
English |
| topic |
Extraction (Chemistry) |
| spellingShingle |
Extraction (Chemistry) Selly Arvinda Rakhman Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| description |
Thesis (M.Sc., Applied Chemistry)--Prince of Songkla University, 2020 |
| author2 |
Weeraya Khummueng |
| author_facet |
Weeraya Khummueng Selly Arvinda Rakhman |
| format |
Theses and Dissertations |
| author |
Selly Arvinda Rakhman |
| author_sort |
Selly Arvinda Rakhman |
| title |
Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| title_short |
Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| title_full |
Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| title_fullStr |
Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| title_full_unstemmed |
Green Synthesis of Silver and Zinc Oxide Nanoparticles using Mimusops elengi Linn. Leaf Extract and Cytotoxicity |
| title_sort |
green synthesis of silver and zinc oxide nanoparticles using mimusops elengi linn. leaf extract and cytotoxicity |
| publisher |
Prince of Songkla University |
| publishDate |
2023 |
| url |
http://kb.psu.ac.th/psukb/handle/2016/19120 |
| _version_ |
1784859627800756224 |