A 32 kb critical region excluding Y402H in CFH mediates risk for age-related macular degeneration

by Sivakumaran, T.A., Igo Jr., R.P., Kidd, J.M., Itsara, A., Kopplin, L.J., Chen, W., Hagstrom, S.A., Peachey, N.S., Francis, P.J., Klein, M.L., Chew, E.Y., Ramprasad, V.L., Tay, W.-T., Mitchell, P., Seielstad, M., Stambolian, D.E., Edwards, A.O., Lee, K.E., Leontiev, D.V., Jun, G., Wang, Y., Tian, L., Qiu, F., Henning, A.K., LaFramboise, T., Sen, P., Aarthi, M., George, R., Raman, R., Das, M.K., Vijaya, L., Kumaramanickavel, G., Wong, T.Y., Swaroop, A., Abecasis, G.R., Klein, R., Klein, B.E.K., Nickerson, D.A., Eichler, E.E., Iyengar, S.K.
Published 2014

Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis

by Holliday, E.G., Smith, A.V., Cornes, B.K., Buitendijk, G.H.S., Jensen, R.A., Sim, X., Aspelund, T., Aung, T., Baird, P.N., Boerwinkle, E., Cheng, C.Y., van Duijn, C.M., Eiriksdottir, G., Gudnason, V., Harris, T., Hewitt, A.W., Inouye, M., Jonasson, F., Klein, B.E.K., Launer, L., Li, X., Liew, G., Lumley, T., McElduff, P., McKnight, B., Mitchell, P., Psaty, B.M., Rochtchina, E., Rotter, J.I., Scott, R.J., Tay, W., Taylor, K., Teo, Y.Y., Uitterlinden, A.G., Viswanathan, A., Xie, S., Vingerling, J.R., Klaver, C.C.W., Tai, E.S., Siscovick, D., Klein, R., Cotch, M.F., Wong, T.Y., Attia, J., Wang, J.J.
Published 2014

Genome-Wide Association Study of Retinopathy in Individuals without Diabetes

by Jensen, R.A., Sim, X., Li, X., Cotch, M.F., Ikram, M.K., Holliday, E.G., Eiriksdottir, G., Harris, T.B., Jonasson, F., Klein, B.E.K., Launer, L.J., Smith, A.V., Boerwinkle, E., Cheung, N., Hewitt, A.W., Liew, G., Mitchell, P., Wang, J.J., Attia, J., Scott, R., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Taylor, K., Hofman, A., de Jong, P.T.V.M., Rivadeneira, F., Uitterlinden, A.G., Tay, W.-T., Teo, Y.Y., Seielstad, M., Liu, J., Cheng, C.-Y., Saw, S.-M., Aung, T., Ganesh, S.K., O'Donnell, C.J., Nalls, M.A., Wiggins, K.L., Kuo, J.Z., van Duijn, C.M., Gudnason, V., Klein, R., Siscovick, D.S., Rotter, J.I., Tai, E.S., Vingerling, J., Wong, T.Y.
Published 2014

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

by Simpson C.L., Wojciechowski R., Oexle K., Murgia F., Portas L., Li X., Virginie J.M.V., Vitart V., Schache M., Mohsen Hosseini S., Hysi P.G., Raffel L.J., Cotch M.F., Chew E., Klein B.E.K., Klein R., Wong T.Y., Van Duijn C.M., Mitchell P., Saw S.M., Fossarello M., Wang J.J., Polašek O., Campbell H., Rudan I., Oostra B.A., Uitterlinden A.G., Hofman A., Rivadeneira F., Amin N., Karssen L.C., Vingerling J.R., Döring A., Bettecken T., Bencic G., Gieger C., Wichmann H.-E., Wilson J.F., Venturini C., Fleck B., Cumberland P.M., Rahi J.S., Hammond C.J., Hayward C., Wright A.F., Paterson A.D., Baird P.N., Klaver C.C.W., Rotter J.I., Pirastu M., Meitinger T., Bailey-Wilson J.E., Stambolian D.
Published 2018

Genetic Loci for Retinal Arteriolar Microcirculation

by Sim, X., Jensen, R.A., Ikram, M.K., Cotch, M.F., Li, X., MacGregor, S., Xie, J., Smith, A.V., Boerwinkle, E., Mitchell, P., Klein, R., Klein, B.E.K., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., de Jong, P.T.V.M., Hofman, A., Rivadeneira, F., Uitterlinden, A.G., van Duijn, C.M., Aspelund, T., Eiriksdottir, G., Harris, T.B., Jonasson, F., Launer, L.J., Attia, J., Baird, P.N., Harrap, S., Holliday, E.G., Inouye, M., Rochtchina, E., Scott, R.J., Viswanathan, A., Li, G., Smith, N.L., Wiggins, K.L., Kuo, J.Z., Taylor, K.D., Hewitt, A.W., Martin, N.G., Montgomery, G.W., Sun, C., Young, T.L., Mackey, D.A., van Zuydam, N.R., Doney, A.S.F., Palmer, C.N.A., Morris, A.D., Rotter, J.I., Tai, E.S., Gudnason, V., Vingerling, J.R., Siscovick, D.S., Wang, J.J., Wong, T.Y.
Published 2014

Common variants in SOX-2 and congenital cataract genes contribute to age-related nuclear cataract

by Yonova-Doing, E., Zhao, W., Igo, R.P., Wang, C., Sundaresan, P., Lee, K.E., Jun, G.R., Alves, A.C., Chai, X., Chan, A.S.Y., Lee, M.C., Fong, A., Tan, A.G., Khor, C.C., Chew, E.Y., Hysi, P.G., Fan, Q., Chua, J., Chung, J., Liao, J., Colijn, J.M., Burdon, K.P., Fritsche, L.G., Swift, M.K., Hilmy, M.H., Chee, M.L., Tedja, M., Bonnemaijer, P.W.M., Gupta, P., Tan, Q.S., Li, Z., Vithana, E.N., Ravindran, R.D., Chee, S.-P., Shi, Y., Liu, W., Su, X., Sim, X., Shen, Y., Wang, Y.X., Li, H., Tham, Y.-C., Teo, Y.Y., Aung, T., Small, K.S., Mitchell, P., Jonas, J.B., Wong, Tien Yin, Fletcher, A.E., Klaver, C.C.W., Klein, B.E.K., Wang, J.J., Iyengar, S.K., Hammond, C.J., Cheng, C.-Y.
Published 2021

Four novel loci (19q13, 6q24, 12q24, and 5q14) influence the microcirculation In vivo

by Kamran Ikram, M., Xueling, S., Jensen, R.A., Cotch, M.F., Hewitt, A.W., Ikram, M.A., Wang, J.J., Klein, R., Klein, B.E.K., Breteler, M.M.B., Cheung, N., Liew, G., Mitchell, P., Uitterlinden, A.G., Rivadeneira, F., Hofman, A., de Jong, P.T.V.M., van Duijn, C.M., Kao, L., Cheng, C.-Y., Smith, A.V., Glazer, N.L., Lumley, T., McKnight, B., Psaty, B.M., Jonasson, F., Eiriksdottir, G., Aspelund, T., Harris, T.B., Launer, L.J., Taylor, K.D., Li, X., Iyengar, S.K., Xi, Q., Sivakumaran, T.A., MacKey, D.A., MacGregor, S., Martin, N.G., Young, T.L., Bis, J.C., Wiggins, K.L., Heckbert, S.R., Hammond, C.J., Andrew, T., Fahy, S., Attia, J., Holliday, E.G., Scott, R.J., Islam, F.M.A., Rotter, J.I., McAuley, A.K., Boerwinkle, E., Tai, E.S., Gudnason, V., Siscovick, D.S., Vingerling, J.R., Wong, T.Y.
Published 2014

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

by Verhoeven, V.J.M., Hysi, P.G., Wojciechowski, R., Fan, Q., Guggenheim, J.A., Höhn, R., Macgregor, S., Hewitt, A.W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M.K., Buitendijk, G.H.S., Mcmahon, G., Kemp, J.P., Pourcain, B.S., Simpson, C.L., Mäkelä, K.-M., Lehtimäki, T., Kähönen, M., Paterson, A.D., Hosseini, S.M., Wong, H.S., Xu, L., Jonas, J.B., Pärssinen, O., Wedenoja, J., Yip, S.P., Ho, D.W.H., Pang, C.P., Chen, L.J., Burdon, K.P., Craig, J.E., Klein, B.E.K., Klein, R., Haller, T., Metspalu, A., Khor, C.-C., Tai, E.-S., Aung, T., Vithana, E., Tay, W.-T., Barathi, V.A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R.T., Döring, A., Evans, D.M., Timpson, N.J., Verkerk, A.J.M.H., Meitinger, T., Raitakari, O., Hawthorne, F., Spector, T.D., Karssen, L.C., Pirastu, M., Murgia, F., Ang, W., Mishra, A., Montgomery, G.W., Pennell, C.E., Cumberland, P.M., Cotlarciuc, I., Mitchell, P., Wang, J.J., Schache, M., Janmahasathian, S., Igo Jr., R.P., Lass, J.H., Chew, E., Iyengar, S.K., Gorgels, T.G.M.F., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Vatavuk, Z., Wilson, J.F., Fleck, B., Zeller, T., Mirshahi, A., Müller, C., Uitterlinden, A.G., Rivadeneira, F., Vingerling, J.R., Hofman, A., Oostra, B.A., Amin, N., Bergen, A.A.B., Teo, Y.-Y., Rahi, J.S., Vitart, V., Williams, C., Baird, P.N., Wong, T.-Y., Oexle, K., Pfeiffer, N., Mackey, D.A., Young, T.L., Van Duijn, C.M., Saw, S.-M., Bailey-Wilson, J.E., Stambolian, D., Klaver, C.C., Hammond, C.J.
Published 2014

Meta-analysis of gene-environment-wide association scans accounting for education level identifies additional loci for refractive error

by Fan Q., Verhoeven V.J.M., Wojciechowski R., Barathi V.A., Hysi P.G., Guggenheim J.A., Hohn R., Vitart V., Khawaja A.P., Yamashiro K., Hosseini S.M., Lehtimaki T., Lu Y., Haller T., Xie J., Delcourt C., Pirastu M., Wedenoja J., Gharahkhani P., Venturini C., Miyake M., Hewitt A.W., Guo X., Mazur J., Huffman J.E., Williams K.M., Polasek O., Campbell H., Rudan I., Vatavuk Z., Wilson J.F., Joshi P.K., McMahon G., St Pourcain B., Evans D.M., Simpson C.L., Schwantes-An T.-H., Igo R.P., Mirshahi A., Cougnard-Gregoire A., Bellenguez C., Blettner M., Raitakari O., Kahonen M., Seppala I., Zeller T., Meitinger T., Ried J.S., Gieger C., Portas L., Van Leeuwen E.M., Amin N., Uitterlinden A.G., Rivadeneira F., Hofman A., Vingerling J.R., Wang Y.X., Wang X., Tai-Hui Boh E., Ikram M.K., Sabanayagam C., Gupta P., Tan V., Zhou L., Ho C.E.H., Lim W., Beuerman R.W., Siantar R., Tai E.-S., Vithana E., Mihailov E., Khor C.-C., Hayward C., Luben R.N., Foster P.J., Klein B.E.K., Klein R., Wong H.-S., Mitchell P., Metspalu A., Aung T., Young T.L., He M., Parssinen O., Van Duijn C.M., Jin Wang J., Williams C., Jonas J.B., Teo Y.-Y., MacKey D.A., Oexle K., Yoshimura N., Paterson A.D., Pfeiffer N., Wong T.-Y., Baird P.N., Stambolian D., Wilson J.E.B., Cheng C.-Y., Hammond C.J., Klaver C.C.W., Saw S.-M., Rahi J.S., Korobelnik J.-F., Kemp J.P., Timpson N.J., Smith G.D., Craig J.E., Burdon K.P., Fogarty R.D., Iyengar S.K., Chew E., Janmahasatian S., Martin N.G., MacGregor S., Xu L., Schache M., Nangia V., Panda-Jonas S., Wright A.F., Fondran J.R., Lass J.H., Feng S., Zhao J.H., Khaw K.-T., Wareham N.J., Rantanen T., Kaprio J., Pang C.P., Chen L.J., Tam P.O., Jhanji V., Young A.L., Doring A., Raffel L.J., Cotch M.-F., Li X., Yip S.P., Yap M.K.H., Biino G., Vaccargiu S., Fossarello M., Fleck B., Yazar S., Tideman J.W.L., Tedja M., Deangelis M.M., Morrison M., Farrer L., Zhou X., Chen W., Mizuki N., Meguro A., Makela K.M.
Published 2020

Seven new loci associated with age-related macular degeneration

by Fritsche, L.G., Chen, W., Schu, M., Yaspan, B.L., Yu, Y., Thorleifsson, G., Zack, D.J., Arakawa, S., Cipriani, V., Ripke, S., Igo, R.P., Buitendijk, G.H.S., Sim, X., Weeks, D.E., Guymer, R.H., Merriam, J.E., Francis, P.J., Hannum, G., Agarwal, A., Armbrecht, A.M., Audo, I., Aung, T., Barile, G.R., Benchaboune, M., Bird, A.C., Bishop, P.N., Branham, K.E., Brooks, M., Brucker, A.J., Cade, W.H., Cain, M.S., Campochiaro, P.A., Chan, C.-C., Cheng, C.-Y., Chew, E.Y., Chin, K.A., Chowers, I., Clayton, D.G., Cojocaru, R., Conley, Y.P., Cornes, B.K., Daly, M.J., Dhillon, B., Edwards, A.O., Evangelou, E., Fagerness, J., Ferreyra, H.A., Friedman, J.S., Geirsdottir, A., George, R.J., Gieger, C., Gupta, N., Hagstrom, S.A., Harding, S.P., Haritoglou, C., Heckenlively, J.R., Holz, F.G., Hughes, G., Ioannidis, J.P.A., Ishibashi, T., Joseph, P., Jun, G., Kamatani, Y., Katsanis, N., N Keilhauer, C., Khan, J.C., Kim, I.K., Kiyohara, Y., Klein, B.E.K., Klein, R., Kovach, J.L., Kozak, I., Lee, C.J., Lee, K.E., Lichtner, P., Lotery, A.J., Meitinger, T., Mitchell, P., Mohand-Saïd, S., Moore, A.T., Morgan, D.J., Morrison, M.A., Myers, C.E., Naj, A.C., Nakamura, Y., Okada, Y., Orlin, A., Ortube, M.C., Othman, M.I., Pappas, C., Park, K.H., Pauer, G.J.T., Peachey, N.S., Poch, O., Priya, R.R., Reynolds, R., Richardson, A.J., Ripp, R., Rudolph, G., Ryu, E., Sahel, J.-A., Schaumberg, D.A., Scholl, H.P.N., Schwartz, S.G., Scott, W.K., Shahid, H., Sigurdsson, H., Silvestri, G., Sivakumaran, T.A., Smith, R.T., Sobrin, L., Souied, E.H., Stambolian, D.E., Stefansson, H., Sturgill-Short, G.M., Takahashi, A., Tosakulwong, N., Truitt, B.J., Tsironi, E.E., Uitterlinden, A.G., Van Duijn, C.M., Vijaya, L., Vingerling, J.R., Vithana, E.N., Webster, A.R., Wichmann, H.-E., Winkler, T.W., Wong, T.Y., Wright, A.F., Zelenika, D., Zhang, M., Zhao, L., Zhang, K., Klein, M.L., Hageman, G.S., Lathrop, G.M., Stefansson, K., Allikmets, R., Baird, P.N., Gorin, M.B., Wang, J.J., Klaver, C.C.W., Seddon, J.M., Pericak-Vance, M.A., Iyengar, S.K., Yates, J.R.W., Swaroop, A., Weber, B.H.F., Kubo, M., Deangelis, M.M., Léveillard, T., Thorsteinsdottir, U., Haines, J.L., Farrer, L.A., Heid, I.M., Abecasis, G.R.
Published 2014