Linkage analysis of quantitative refraction and refractive errors in the beaver dam eye study

by Klein, A.P., Duggal, P., Lee, K.E., Cheng, C.-Y., Klein, R., Bailey-Wilson, J.E., Klein, B.E.K.
Published 2014

EPHA2 is associated with age-related cortical cataract in mice and humans

by Jun G., Guo H., Klein B.E.K., Klein R., Jie J.W., Mitchell P., Miao H., Lee K.E., Joshi T., Buck M., Chugha P., Bardenstein D., Klein A.P., Bailey-Wilson J.E., Gong X., Spector T.D., Andrew T., Hammond C.J., Elston R.C., Iyengar S.K., Wang B.
Published 2019

Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

by Simpson C.L., Wojciechowski R., Oexle K., Murgia F., Portas L., Li X., Virginie J.M.V., Vitart V., Schache M., Mohsen Hosseini S., Hysi P.G., Raffel L.J., Cotch M.F., Chew E., Klein B.E.K., Klein R., Wong T.Y., Van Duijn C.M., Mitchell P., Saw S.M., Fossarello M., Wang J.J., Polašek O., Campbell H., Rudan I., Oostra B.A., Uitterlinden A.G., Hofman A., Rivadeneira F., Amin N., Karssen L.C., Vingerling J.R., Döring A., Bettecken T., Bencic G., Gieger C., Wichmann H.-E., Wilson J.F., Venturini C., Fleck B., Cumberland P.M., Rahi J.S., Hammond C.J., Hayward C., Wright A.F., Paterson A.D., Baird P.N., Klaver C.C.W., Rotter J.I., Pirastu M., Meitinger T., Bailey-Wilson J.E., Stambolian D.
Published 2018

Meta-analysis of genome-wide association studies in five cohorts reveals common variants in RBFOX1, a regulator of tissue-specific splicing, associated with refractive error

by Stambolian, D., Wojciechowski, R., Oexle, K., Pirastu, M., Li, X., Raffe, L.J., Cotch, M.F., Chew, E.Y., Klein, B., Klein, R., Wong, T.Y., Simpson, C.L., Klaver, C.C.W., van Duijn, C.M., Verhoeven, V.J.M., Baird, P.N., Vitart, V., Paterson, A.D., Mitchell, P., Saw, S.M., Fossarello, M., Kazmierkiewicz, K., Murgia, F., Portas, L., Schache, M., Richardson, A., Xie, J., Wang, J.J., Rochtchina, E., Viswanathan, A.C., Hayward, C., Wright, A.F., Polašek, O., Campbell, H., Rudan, I., Oostra, B.A., Uitterlinden, A.G., Hofman, A., Rivadeneira, F., Amin, N., Karssen, L.C., Vingerling, J.R., Hosseini, S.M., Döring, A., Bettecken, T., Vatavuk, Z., Gieger, C., Wichmann, H.-E., Wilson, J.F., Fleck, B., Foster, P.J., Topouzis, F., McGuffin, P., Sim, X., Inouye, M., Holliday, E.G., Attia, J., Scott, R.J., Rotter, J.I., Meitinger, T., Bailey-Wilson, J.E.
Published 2014

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

by Li Q., Wojciechowski R., Simpson C.L., Hysi P.G., Verhoeven V.J.M., Ikram M.K., Höhn R., Vitart V., Hewitt A.W., Oexle K., Mäkelä K.-M., Ho D.W.H., Chew E., Mihailov E., Smith G.D., Biino G., Rudan I., Seppala I., Kaprio J., Craig J.E., Polling J.R., MacGregor S., Tideman J.-W., Fondran J.R., Wang J.J., Liao J., Zhao J.H., Xie J., Bailey Wilson J.E., Burdon K.P., Khaw K.-T., Yamashiro K., Pirastu M., Portas L., Farrer L., Raffel L.J., Chen L.J., Xu L., Deangelis M.M., Morrison M., Schache M., Cotch M.-F., Miyake M., Fan Q., Fossarello M., He M., Yoshimura N., Wareham N.J., Mizuki N., Pfeiffer N., Polasek O., Tam P.O., Foster P.J., Chen P., Cheng C.-Y., Gharahkhani P., Fogarty R.D., Luben R.N., Igo R.P., Jr., Klein R., Mohsen Hosseini S., Janmahasatian S., Feng S., Panda-Jonas S., St Pourcain B., Iyengar S.K., Lass J.H., Rantanen T., Haller T., Nangia V., Jhanji V., Chen W., Zhou X., Guo X., Li X., McMahon G., Vatavuk Z., The CREAM consortium, Kemp J.P., Northstone K., Rahi J.S., Cumberland P.M., Martin N.G., Sanfilippo P.G., Lu Y., Wang Y.X., Hayward C., Polašek O., Campbell H., Bencic G., Wright A.F., Wedenoja J., Zeller T., Schillert A., Mirshahi A., Lackner K., Yip S.P., Yap M.K.H., Ried J.S., Gieger C., Murgia F., Wilson J.F., Fleck B., Yazar S., Vingerling J.R., Hofman A., Uitterlinden A., Rivadeneira F., Amin N., Karssen L., Oostra B.A., Zhou X., Teo Y.-Y., Tai E.S., Vithana E., Barathi V., Zheng Y., Siantar R.G., Neelam K., Shin Y., Lam J., Yonova-Doing E., Venturini C., Hosseini S.M., Wong H.-S., Lehtimäki T., Kähönen M., Raitakari O., Timpson N.J., Evans D.M., Khor C.-C., Aung T., Young T.L., Mitchell P., Klein B., van Duijn C.M., Meitinger T., Jonas J.B., Baird P.N., Mackey D.A., Wong T.Y., Saw S.-M., Pärssinen O., Stambolian D., Hammond C.J., Klaver C.C.W., Williams C., Paterson A.D., Bailey-Wilson J.E., Guggenheim J.A., Meguro A., Young A.L., Veluchamy A.B., Metspalu A., Döring A., Khawaja A.P., Klein B.E., Pourcain B.S., Delcourt C., Maubaret C., Pang C.P.
Published 2020

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

by Verhoeven, V.J.M., Hysi, P.G., Saw, S.-M., Vitart, V., Mirshahi, A., Guggenheim, J.A., Cotch, M.F., Yamashiro, K., Baird, P.N., Mackey, D.A., Wojciechowski, R., Kamran Ikram, M., Hewitt, A.W., Duggal, P., Janmahasatian, S., Khor, C.-C., Fan, Q., Zhou, X., Young, T.L., Tai, E.-S., Goh, L.-K., Li, Y.-J., Aung, T., Vithana, E., Teo, Y.-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Campbell, H., Wilson, J.F., Fleck, B.W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St. Pourcain, B., Lu, Y., Rahi, J.S., Cumberland, P.M., Bhattacharya, S., Simpson, C.L., Atwood, L.D., Li, X., Raffel, L.J., Murgia, F., Portas, L., Despriet, D.D.G., Van Koolwijk, L.M.E., Wolfram, C., Lackner, K.J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B.E., Meitinger, T., Spector, T.D., Oostra, B.A., Smith, A.V., De Jong, P.T.V.M., Hofman, A., Amin, N., Karssen, L.C., Rivadeneira, F., Vingerling, J.R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A.G., Williams, C., Zeller, T., Castagné, R., Oexle, K., Van Duijn, C.M., Iyengar, S.K., Mitchell, P., Wang, J.J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J.E., Stambolian, D., Wong, T.-Y., Hammond, C.J., Klaver, C.C.W.
Published 2014

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

by Verhoeven, V.J.M., Hysi, P.G., Wojciechowski, R., Fan, Q., Guggenheim, J.A., Höhn, R., Macgregor, S., Hewitt, A.W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M.K., Buitendijk, G.H.S., Mcmahon, G., Kemp, J.P., Pourcain, B.S., Simpson, C.L., Mäkelä, K.-M., Lehtimäki, T., Kähönen, M., Paterson, A.D., Hosseini, S.M., Wong, H.S., Xu, L., Jonas, J.B., Pärssinen, O., Wedenoja, J., Yip, S.P., Ho, D.W.H., Pang, C.P., Chen, L.J., Burdon, K.P., Craig, J.E., Klein, B.E.K., Klein, R., Haller, T., Metspalu, A., Khor, C.-C., Tai, E.-S., Aung, T., Vithana, E., Tay, W.-T., Barathi, V.A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R.T., Döring, A., Evans, D.M., Timpson, N.J., Verkerk, A.J.M.H., Meitinger, T., Raitakari, O., Hawthorne, F., Spector, T.D., Karssen, L.C., Pirastu, M., Murgia, F., Ang, W., Mishra, A., Montgomery, G.W., Pennell, C.E., Cumberland, P.M., Cotlarciuc, I., Mitchell, P., Wang, J.J., Schache, M., Janmahasathian, S., Igo Jr., R.P., Lass, J.H., Chew, E., Iyengar, S.K., Gorgels, T.G.M.F., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Vatavuk, Z., Wilson, J.F., Fleck, B., Zeller, T., Mirshahi, A., Müller, C., Uitterlinden, A.G., Rivadeneira, F., Vingerling, J.R., Hofman, A., Oostra, B.A., Amin, N., Bergen, A.A.B., Teo, Y.-Y., Rahi, J.S., Vitart, V., Williams, C., Baird, P.N., Wong, T.-Y., Oexle, K., Pfeiffer, N., Mackey, D.A., Young, T.L., Van Duijn, C.M., Saw, S.-M., Bailey-Wilson, J.E., Stambolian, D., Klaver, C.C., Hammond, C.J.
Published 2014

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

by Cheng, C.-Y., Schache, M., Ikram, M.K., Young, T.L., Guggenheim, J.A., Vitart, V., MacGregor, S., Verhoeven, V.J.M., Barathi, V.A., Liao, J., Hysi, P.G., Bailey-Wilson, J.E., St. Pourcain, B., Kemp, J.P., McMahon, G., Timpson, N.J., Evans, D.M., Montgomery, G.W., Mishra, A., Wang, Y.X., Wang, J.J., Rochtchina, E., Polasek, O., Wright, A.F., Amin, N., Van Leeuwen, E.M., Wilson, J.F., Pennell, C.E., Van Duijn, C.M., De Jong, P.T.V.M., Vingerling, J.R., Zhou, X., Chen, P., Li, R., Tay, W.-T., Zheng, Y., Chew, M., Burdon, K.P., Craig, J.E., Iyengar, S.K., Igo Jr., R.P., Lass Jr., J.H., Chew, E.Y., Haller, T., Mihailov, E., Metspalu, A., Wedenoja, J., Simpson, C.L., Wojciechowski, R., Höhn, R., Mirshahi, A., Zeller, T., Pfeiffer, N., Lackner, K.J., Bettecken, T., Meitinger, T., Oexle, K., Pirastu, M., Portas, L., Nag, A., Williams, K.M., Yonova-Doing, E., Klein, R., Klein, B.E., Hosseini, S.M., Paterson, A.D., Makela, K.-M., Lehtimaki, T., Kahonen, M., Raitakari, O., Yoshimura, N., Matsuda, F., Chen, L.J., Pang, C.P., Yip, S.P., Yap, M.K.H., Meguro, A., Mizuki, N., Inoko, H., Foster, P.J., Zhao, J.H., Vithana, E., Tai, E.-S., Fan, Q., Xu, L., Campbell, H., Fleck, B., Rudan, I., Aung, T., Hofman, A., Uitterlinden, A.G., Bencic, G., Khor, C.-C., Forward, H., Pärssinen, O., Mitchell, P., Rivadeneira, F., Hewitt, A.W., Williams, C., Oostra, B.A., Teo, Y.-Y., Hammond, C.J., Stambolian, D., MacKey, D.A., Klaver, C.C.W., Wong, T.-Y., Saw, S.-M., Baird, P.N.
Published 2014

Childhood gene-environment interactions and age-dependent effects of genetic variants associated with refractive error and myopia: The CREAM Consortium

by Fan, Q, Guo, X, Tideman, J.W.L, Williams, K.M, Yazar, S, Hosseini, S.M, Howe, L.D, Pourcain, B.S, Evans, D.M, Timpson, N.J, McMahon, G, Hysi, P.G, Krapohl, E, Wang, Y.X, Jonas, J.B, Baird, P.N, Wang, J.J, Cheng, C.-Y, Teo, Y.-Y, Wong, T.-Y, Ding, X, Wojciechowski, R, Young, T.L, Pärssinen, O, Oexle, K, Pfeiffer, N, Bailey-Wilson, J.E, Paterson, A.D, Klaver, C.C.W, Plomin, R, Hammond, C.J, He, M, Saw, S.-M, Guggenheim, J.A, Meguro, A, Wright, A.F, Hewitt, A.W, Young, A.L, Veluchamy, A.B, Metspalu, A, Döring, A, Khawaja, A.P, Klein, B.E, St Pourcain, B, Fleck, B, Klaver, C.C.W, Hayward, C, Williams, C, Delcourt, C, Pang, C.P, Khor, C.-C, Gieger, C, Simpson, C.L, Van Duijn, C.M, Mackey, D.A, Stambolian, D, Chew, E, Tai, E.-S, Mihailov, E, Smith, G.D, Biino, G, Campbell, H, Rudan, I, Seppälä, I, Kaprio, J, Wilson, J.F, Craig, J.E, Ried, J.S, Korobelnik, J.-F, Fondran, J.R, Liao, J, Zhao, J.H, Xie, J, Kemp, J.P, Lass, J.H, Rahi, J.S, Wedenoja, J, Mäkelä, K.-M, Burdon, K.P, Khaw, K.-T, Yamashiro, K, Chen, L.J, Xu, L, Farrer, L, Ikram, M.K, Deangelis, M.M, Morrison, M, Schache, M, Pirastu, M, Miyake, M, Yap, M.K.H, Fossarello, M, Kähönen, M, Tedja, M.S, Yoshimura, N, Martin, N.G, Wareham, N.J, Mizuki, N, Raitakari, O, Polasek, O, Tam, P.O, Foster, P.J, Mitchell, P, Chen, P, Cumberland, P, Gharahkhani, P, Höhn, R, Fogarty, R.D, Luben, R.N, Igo, R.P, Klein, R, Janmahasatian, S, Yip, S.P, Feng, S, Vaccargiu, S, Panda-Jonas, S, MacGregor, S, Iyengar, S.K, Rantanen, T, Lehtimäki, T, Meitinger, T, Aung, T, Haller, T, Vitart, V, Nangia, V, Verhoeven, V.J.M, Jhanji, V, Zhao, W, Chen, W, Zhou, X, Lu, Y, Vatavuk, Z, The CREAM Consortium
Published 2020

Branched peptide, B2088, disrupts the supramolecular organization of lipopolysaccharides and sensitizes the gram-negative bacteria

by Fan, Q, Guo, X, Tideman, J.W.L, Williams, K.M, Yazar, S, Hosseini, S.M, Howe, L.D, Pourcain, B.S, Evans, D.M, Timpson, N.J, McMahon, G, Hysi, P.G, Krapohl, E, Wang, Y.X, Jonas, J.B, Baird, P.N, Wang, J.J, Cheng, C.-Y, Teo, Y.-Y, Wong, T.-Y, Ding, X, Wojciechowski, R, Young, T.L, Pärssinen, O, Oexle, K, Pfeiffer, N, Bailey-Wilson, J.E, Paterson, A.D, Klaver, C.C.W, Plomin, R, Hammond, C.J, He, M, Saw, S.-M, Guggenheim, J.A, Meguro, A, Wright, A.F, Hewitt, A.W, Young, A.L, Veluchamy, A.B, Metspalu, A, Döring, A, Khawaja, A.P, Klein, B.E, St Pourcain, B, Fleck, B, Klaver, C.C.W, Hayward, C, Williams, C, Delcourt, C, Pang, C.P, Khor, C.-C, Gieger, C, Simpson, C.L, Van Duijn, C.M, Mackey, D.A, Stambolian, D, Chew, E, Tai, E.-S, Mihailov, E, Smith, G.D, Biino, G, Campbell, H, Rudan, I, Seppälä, I, Kaprio, J, Wilson, J.F, Craig, J.E, Ried, J.S, Korobelnik, J.-F, Fondran, J.R, Liao, J, Zhao, J.H, Xie, J, Kemp, J.P, Lass, J.H, Rahi, J.S, Wedenoja, J, Mäkelä, K.-M, Burdon, K.P, Khaw, K.-T, Yamashiro, K, Chen, L.J, Xu, L, Farrer, L, Ikram, M.K, Deangelis, M.M, Morrison, M, Schache, M, Pirastu, M, Miyake, M, Yap, M.K.H, Fossarello, M, Kähönen, M, Tedja, M.S, Yoshimura, N, Martin, N.G, Wareham, N.J, Mizuki, N, Raitakari, O, Polasek, O, Tam, P.O, Foster, P.J, Mitchell, P, Chen, P, Cumberland, P, Gharahkhani, P, Höhn, R, Fogarty, R.D, Luben, R.N, Igo, R.P, Klein, R, Janmahasatian, S, Yip, S.P, Feng, S, Vaccargiu, S, Panda-Jonas, S, MacGregor, S, Iyengar, S.K, Rantanen, T, Lehtimäki, T, Meitinger, T, Aung, T, Haller, T, Vitart, V, Nangia, V, Verhoeven, V.J.M, Jhanji, V, Zhao, W, Chen, W, Zhou, X, Lu, Y, Vatavuk, Z, The CREAM Consortium, Lakshminarayanan, R, Tan, W.X, Aung, T.T, Goh, E.T.L, Muruganantham, N, Li, J, Chang, J.Y.T, Dikshit, N, Saraswathi, P, Lim, R.R, Kang, T.S, Balamuralidhar, V, Sukumaran, B, Verma, C.S, Sivaraman, J, Chaurasia, S.S, Liu, S, Beuerman, R.W
Published 2020

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

by Fan, Q., Pozarickij, A., Tan, N.Y.Q., Guo, X., Verhoeven, V.J.M., Vitart, V., Guggenheim, J.A., Miyake, M., Tideman, J.W.L., Khawaja, A.P., Zhang, L., MacGregor, S., Höhn, R., Chen, P., Biino, G., Wedenoja, J., Saffari, S.E., Tedja, M.S., Xie, J., Lanca, C., Wang, Y.X., Sahebjada, S., Mazur, J., Mirshahi, A., Martin, N.G., Yazar, S., Pennell, C.E., Yap, M., Haarman, A.E.G., Enthoven, C.A., Polling, J.R., Bailey-Wilson, J.E., Veluchamy, A.B., Burdon, K.P., Campbell, H., Chen, L.J., Chew, E.Y., Craig, J.E., Cumberland, P.M., Deangelis, M.M., Delcourt, C., Ding, X., Evans, D.M., Gharahkhani, P., Iglesias, A.I., Haller, T., Han, X., Hoang, Q., Igo, R.P., Iyengar, S.K., Kähönen, M., Kaprio, J., Klein, B.E., Klein, R., Lass, J.H., Lee, K., Lehtimäki, T., Lewis, D.D., Li, Q., Li, S.-M., Lyytikäinen, L.-P., Meguro, A., Metspalu, A., Middlebrooks, C.D., Mizuki, N., Musolf, A.M., Nickels, S., Oexle, K., Pang, C.P., Paterson, A.D., Rahi, J.S., Raitakari, O., Rudan, I., Stambolian, D., Simpson, C.L., Wang, N., Bin Wei, W., Williams, K.M., Wilson, J.F., Wojciechowski, R., Yamashiro, K., Yam, J.C.S., Zhou, X., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Cumberland, P.M., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Fruttiger, M., Gallacher, J.E.J., Garway-Heath, D.F., Gibson, J., Gore, D., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, S.P.T., Lascaratos, G., Lotery, A.J., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rahi, J.S., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Viswanathan, A.C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Hewitt, A.W., Jaddoe, V.W.V., van Duijn, C.M., Hayward, C., Polasek, O., Tai, E.-S., Yoshikatsu, H., Hysi, P.G., Young, T.L., Tsujikawa, A., Wang, J.J., Mitchell, P., Pfeiffer, N., Pärssinen, O., Foster, P.J., Fossarello, M., Yip, S.P., Williams, C., Hammond, C.J., Jonas, J.B., He, M., Mackey, D.A., Wong, T.-Y., Klaver, C.C.W., Saw, S.-M., Baird, P.N., Cheng, C.-Y., Consortium for Refractive Error and Myopia (CREAM)., UK Biobank Eye and Vision Consortium.
Published 2021