Keratoconus-susceptibility gene identification by corneal thickness genome-wide association study and artificial intelligence IBM Watson

by Hosoda, Y., Miyake, M., Meguro, A., Tabara, Y., Iwai, S., Ueda-Arakawa, N., Nakano, E., Mori, Y., Yoshikawa, M., Nakanishi, H., Khor, C.-C., Saw, S.-M., Yamada, R., Matsuda, F., Cheng, C.-Y., Mizuki, N., Tsujikawa, A., Yamashiro, K., Tabara, Y., Kawaguchi, T., Setoh, K., Matsuda, F., Takahashi, Y., Nakayama, T., Kosugi, S., The Nagahama Study Group.
Published 2021

Joint ancestry and association test indicate two distinct pathogenic pathways involved in classical dengue fever and dengue shock syndrome

by Oliveira, M., Lert-itthiporn, W., Cavadas, B., Fernandes, V., Chuansumrit, A., Anunciação, O., Casademont, I., Koeth, F., Penova, M., Tangnararatchakit, K., Khor, C.C., Paul, R., Malasit, P., Matsuda, F., Simon-Lorière, E., Suriyaphol, P., Pereira, L., Sakuntabhai, A.
Published 2021

Genome-wide association studies reveal genetic variants in CTNND2 for high myopia in Singapore Chinese

by Li, Y.-J., Goh, L., Khor, C.-C., Fan, Q., Yu, M., Han, S., Sim, X., Ong, R.T.-H., Wong, T.-Y., Vithana, E.N., Yap, E., Nakanishi, H., Matsuda, F., Ohno-Matsui, K., Yoshimura, N., Seielstad, M., Tai, E.-S., Young, T.L., Saw, S.-M.
Published 2014

CCDC102B confers risk of low vision and blindness in high myopia

by Hosoda, Y, Yoshikawa, M, Miyake, M, Tabara, Y, Shimada, N, Zhao, W, Oishi, A, Nakanishi, H, Hata, M, Akagi, T, Ooto, S, Nagaoka, N, Fang, Y, Kawaguchi, T, Setoh, K, Takahashi, Y, Kosugi, S, Nakayama, T, Ohno-Matsui, K, Cheng, C.-Y, Saw, S.M, Yamada, R, Matsuda, F, Tsujikawa, A, Yamashiro, K
Published 2020

Association of genetic variants on 8p21 and 4q12 with age-related macular degeneration in Asian populations

by Nakata, I., Yamashiro, K., Akagi-Kurashige, Y., Miyake, M., Kumagai, K., Tsujikawa, A., Liu, K., Chen, L.J., Liu, D.T.L., Lai, T.Y.Y., Sakurada, Y., Yoneyama, S., Cheng, C.-Y., Cackett, P., Yeo, I.Y., Tay, W.T., Cornes, B.K., Vithana, E.N., Aung, T., Matsuo, K., Matsuda, F., Wong, T.-Y., Iijima, H., Pang, C.P., Yoshimura, N.
Published 2014

A genome-wide association study identified a novel genetic loci STON1-GTF2A1L/LHCGR/FSHR for bilaterality of neovascular age-related macular degeneration

by Kawashima-Kumagai, K, Yamashiro, K, Yoshikawa, M, Miyake, M, Ming, G.C.C, Fan, Q, Koh, J.Y, Saito, M, Sugahara-Kuroda, M, Oishi, M, Akagi-Kurashige, Y, Nakata, I, Nakanishi, H, Gotoh, N, Oishi, A, Tamura, H, Ooto, S, Tsujikawa, A, Kurimoto, Y, Sekiryu, T, Matsuda, F, Khor, C.-C, Cheng, C.-Y, Wong, T.Y, Yoshimura, N
Published 2020

Genome-wide association study identifies ZFHX1B as a susceptibility locus for severe myopia

by Khor, C.C., Miyake, M., Chen, L.J., Shi, Y., Barathi, V.A., Qiao, F., Nakata, I., Yamashiro, K., Zhou, X., Tam, P.O.S., Cheng, C.-Y., Tai, E.S., Vithana, E.N., Aung, T., Teo, Y.-Y., Wong, T.-Y., Moriyama, M., Ohno-Matsui, K., Mochizuki, M., Matsuda, F., Yong, R.Y.Y., Yap, E.P.H., Yang, Z., Pang, C.P., Saw, S.-M., Yoshimura, N.
Published 2014

Genetic variants on chromosome 1q41 influence ocular axial length and high myopia

by Fan, Q., Barathi, V.A., Cheng, C.-Y., Zhou, X., Meguro, A., Nakata, I., Khor, C.-C., Goh, L.-K., Li, Y.-J., Lim, W., Ho, C.E.H., Hawthorne, F., Zheng, Y., Chua, D., Inoko, H., Yamashiro, K., Ohno-Matsui, K., Matsuo, K., Matsuda, F., Vithana, E., Seielstad, M., Mizuki, N., Beuerman, R.W., Tai, E., Yoshimura, N., Aung, T., Young, T.L., Wong, T.-Y., Teo, Y.-Y., Saw, S.-M.
Published 2014

Genome-wide association analyses identify two susceptibility loci for pachychoroid disease central serous chorioretinopathy

by Hosoda, Y., Miyake, M., Schellevis, R.L., Boon, C.J.F., Hoyng, C.B., Miki, A., Meguro, A., Sakurada, Y., Yoneyama, S., Takasago, Y., Hata, M., Muraoka, Y., Nakanishi, H., Oishi, A., Ooto, S., Tamura, H., Uji, A., Miyata, M., Takahashi, A., Ueda-Arakawa, N., Tajima, A., Sato, T., Mizuki, N., Shiragami, C., Iida, T., Khor, C.C., Wong, T.Y., Yamada, R., Honda, S., de Jong, E.K., Hollander, A.I., Matsuda, F., Yamashiro, K., Tsujikawa, A.
Published 2021

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

by Verhoeven, V.J.M., Hysi, P.G., Saw, S.-M., Vitart, V., Mirshahi, A., Guggenheim, J.A., Cotch, M.F., Yamashiro, K., Baird, P.N., Mackey, D.A., Wojciechowski, R., Kamran Ikram, M., Hewitt, A.W., Duggal, P., Janmahasatian, S., Khor, C.-C., Fan, Q., Zhou, X., Young, T.L., Tai, E.-S., Goh, L.-K., Li, Y.-J., Aung, T., Vithana, E., Teo, Y.-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Campbell, H., Wilson, J.F., Fleck, B.W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St. Pourcain, B., Lu, Y., Rahi, J.S., Cumberland, P.M., Bhattacharya, S., Simpson, C.L., Atwood, L.D., Li, X., Raffel, L.J., Murgia, F., Portas, L., Despriet, D.D.G., Van Koolwijk, L.M.E., Wolfram, C., Lackner, K.J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B.E., Meitinger, T., Spector, T.D., Oostra, B.A., Smith, A.V., De Jong, P.T.V.M., Hofman, A., Amin, N., Karssen, L.C., Rivadeneira, F., Vingerling, J.R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A.G., Williams, C., Zeller, T., Castagné, R., Oexle, K., Van Duijn, C.M., Iyengar, S.K., Mitchell, P., Wang, J.J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J.E., Stambolian, D., Wong, T.-Y., Hammond, C.J., Klaver, C.C.W.
Published 2014

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error

by Cheng, C.-Y., Schache, M., Ikram, M.K., Young, T.L., Guggenheim, J.A., Vitart, V., MacGregor, S., Verhoeven, V.J.M., Barathi, V.A., Liao, J., Hysi, P.G., Bailey-Wilson, J.E., St. Pourcain, B., Kemp, J.P., McMahon, G., Timpson, N.J., Evans, D.M., Montgomery, G.W., Mishra, A., Wang, Y.X., Wang, J.J., Rochtchina, E., Polasek, O., Wright, A.F., Amin, N., Van Leeuwen, E.M., Wilson, J.F., Pennell, C.E., Van Duijn, C.M., De Jong, P.T.V.M., Vingerling, J.R., Zhou, X., Chen, P., Li, R., Tay, W.-T., Zheng, Y., Chew, M., Burdon, K.P., Craig, J.E., Iyengar, S.K., Igo Jr., R.P., Lass Jr., J.H., Chew, E.Y., Haller, T., Mihailov, E., Metspalu, A., Wedenoja, J., Simpson, C.L., Wojciechowski, R., Höhn, R., Mirshahi, A., Zeller, T., Pfeiffer, N., Lackner, K.J., Bettecken, T., Meitinger, T., Oexle, K., Pirastu, M., Portas, L., Nag, A., Williams, K.M., Yonova-Doing, E., Klein, R., Klein, B.E., Hosseini, S.M., Paterson, A.D., Makela, K.-M., Lehtimaki, T., Kahonen, M., Raitakari, O., Yoshimura, N., Matsuda, F., Chen, L.J., Pang, C.P., Yip, S.P., Yap, M.K.H., Meguro, A., Mizuki, N., Inoko, H., Foster, P.J., Zhao, J.H., Vithana, E., Tai, E.-S., Fan, Q., Xu, L., Campbell, H., Fleck, B., Rudan, I., Aung, T., Hofman, A., Uitterlinden, A.G., Bencic, G., Khor, C.-C., Forward, H., Pärssinen, O., Mitchell, P., Rivadeneira, F., Hewitt, A.W., Williams, C., Oostra, B.A., Teo, Y.-Y., Hammond, C.J., Stambolian, D., MacKey, D.A., Klaver, C.C.W., Wong, T.-Y., Saw, S.-M., Baird, P.N.
Published 2014