Genome-wide meta-analysis of myopia and hyperopia provides evidence for replication of 11 loci

by Simpson C.L., Wojciechowski R., Oexle K., Murgia F., Portas L., Li X., Virginie J.M.V., Vitart V., Schache M., Mohsen Hosseini S., Hysi P.G., Raffel L.J., Cotch M.F., Chew E., Klein B.E.K., Klein R., Wong T.Y., Van Duijn C.M., Mitchell P., Saw S.M., Fossarello M., Wang J.J., Polašek O., Campbell H., Rudan I., Oostra B.A., Uitterlinden A.G., Hofman A., Rivadeneira F., Amin N., Karssen L.C., Vingerling J.R., Döring A., Bettecken T., Bencic G., Gieger C., Wichmann H.-E., Wilson J.F., Venturini C., Fleck B., Cumberland P.M., Rahi J.S., Hammond C.J., Hayward C., Wright A.F., Paterson A.D., Baird P.N., Klaver C.C.W., Rotter J.I., Pirastu M., Meitinger T., Bailey-Wilson J.E., Stambolian D.
Published 2018

Genome-wide association meta-analysis of corneal curvature identifies novel loci and shared genetic influences across axial length and refractive error

by Fan, Q., Pozarickij, A., Tan, N.Y.Q., Guo, X., Verhoeven, V.J.M., Vitart, V., Guggenheim, J.A., Miyake, M., Tideman, J.W.L., Khawaja, A.P., Zhang, L., MacGregor, S., Höhn, R., Chen, P., Biino, G., Wedenoja, J., Saffari, S.E., Tedja, M.S., Xie, J., Lanca, C., Wang, Y.X., Sahebjada, S., Mazur, J., Mirshahi, A., Martin, N.G., Yazar, S., Pennell, C.E., Yap, M., Haarman, A.E.G., Enthoven, C.A., Polling, J.R., Bailey-Wilson, J.E., Veluchamy, A.B., Burdon, K.P., Campbell, H., Chen, L.J., Chew, E.Y., Craig, J.E., Cumberland, P.M., Deangelis, M.M., Delcourt, C., Ding, X., Evans, D.M., Gharahkhani, P., Iglesias, A.I., Haller, T., Han, X., Hoang, Q., Igo, R.P., Iyengar, S.K., Kähönen, M., Kaprio, J., Klein, B.E., Klein, R., Lass, J.H., Lee, K., Lehtimäki, T., Lewis, D.D., Li, Q., Li, S.-M., Lyytikäinen, L.-P., Meguro, A., Metspalu, A., Middlebrooks, C.D., Mizuki, N., Musolf, A.M., Nickels, S., Oexle, K., Pang, C.P., Paterson, A.D., Rahi, J.S., Raitakari, O., Rudan, I., Stambolian, D., Simpson, C.L., Wang, N., Bin Wei, W., Williams, K.M., Wilson, J.F., Wojciechowski, R., Yamashiro, K., Yam, J.C.S., Zhou, X., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Cumberland, P.M., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Fruttiger, M., Gallacher, J.E.J., Garway-Heath, D.F., Gibson, J., Gore, D., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, S.P.T., Lascaratos, G., Lotery, A.J., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rahi, J.S., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Viswanathan, A.C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Hewitt, A.W., Jaddoe, V.W.V., van Duijn, C.M., Hayward, C., Polasek, O., Tai, E.-S., Yoshikatsu, H., Hysi, P.G., Young, T.L., Tsujikawa, A., Wang, J.J., Mitchell, P., Pfeiffer, N., Pärssinen, O., Foster, P.J., Fossarello, M., Yip, S.P., Williams, C., Hammond, C.J., Jonas, J.B., He, M., Mackey, D.A., Wong, T.-Y., Klaver, C.C.W., Saw, S.-M., Baird, P.N., Cheng, C.-Y., Consortium for Refractive Error and Myopia (CREAM)., UK Biobank Eye and Vision Consortium.
Published 2021

Large scale international replication and meta-analysis study confirms association of the 15q14 locus with myopia. The CREAM consortium

by Verhoeven, V.J.M., Hysi, P.G., Saw, S.-M., Vitart, V., Mirshahi, A., Guggenheim, J.A., Cotch, M.F., Yamashiro, K., Baird, P.N., Mackey, D.A., Wojciechowski, R., Kamran Ikram, M., Hewitt, A.W., Duggal, P., Janmahasatian, S., Khor, C.-C., Fan, Q., Zhou, X., Young, T.L., Tai, E.-S., Goh, L.-K., Li, Y.-J., Aung, T., Vithana, E., Teo, Y.-Y., Tay, W., Sim, X., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Campbell, H., Wilson, J.F., Fleck, B.W., Nakata, I., Yoshimura, N., Yamada, R., Matsuda, F., Ohno-Matsui, K., Nag, A., McMahon, G., St. Pourcain, B., Lu, Y., Rahi, J.S., Cumberland, P.M., Bhattacharya, S., Simpson, C.L., Atwood, L.D., Li, X., Raffel, L.J., Murgia, F., Portas, L., Despriet, D.D.G., Van Koolwijk, L.M.E., Wolfram, C., Lackner, K.J., Tönjes, A., Mägi, R., Lehtimäki, T., Kähönen, M., Esko, T., Metspalu, A., Rantanen, T., Pärssinen, O., Klein, B.E., Meitinger, T., Spector, T.D., Oostra, B.A., Smith, A.V., De Jong, P.T.V.M., Hofman, A., Amin, N., Karssen, L.C., Rivadeneira, F., Vingerling, J.R., Eiríksdóttir, G., Gudnason, V., Döring, A., Bettecken, T., Uitterlinden, A.G., Williams, C., Zeller, T., Castagné, R., Oexle, K., Van Duijn, C.M., Iyengar, S.K., Mitchell, P., Wang, J.J., Höhn, R., Pfeiffer, N., Bailey-Wilson, J.E., Stambolian, D., Wong, T.-Y., Hammond, C.J., Klaver, C.C.W.
Published 2014

Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia

by Verhoeven, V.J.M., Hysi, P.G., Wojciechowski, R., Fan, Q., Guggenheim, J.A., Höhn, R., Macgregor, S., Hewitt, A.W., Nag, A., Cheng, C.-Y., Yonova-Doing, E., Zhou, X., Ikram, M.K., Buitendijk, G.H.S., Mcmahon, G., Kemp, J.P., Pourcain, B.S., Simpson, C.L., Mäkelä, K.-M., Lehtimäki, T., Kähönen, M., Paterson, A.D., Hosseini, S.M., Wong, H.S., Xu, L., Jonas, J.B., Pärssinen, O., Wedenoja, J., Yip, S.P., Ho, D.W.H., Pang, C.P., Chen, L.J., Burdon, K.P., Craig, J.E., Klein, B.E.K., Klein, R., Haller, T., Metspalu, A., Khor, C.-C., Tai, E.-S., Aung, T., Vithana, E., Tay, W.-T., Barathi, V.A., Chen, P., Li, R., Liao, J., Zheng, Y., Ong, R.T., Döring, A., Evans, D.M., Timpson, N.J., Verkerk, A.J.M.H., Meitinger, T., Raitakari, O., Hawthorne, F., Spector, T.D., Karssen, L.C., Pirastu, M., Murgia, F., Ang, W., Mishra, A., Montgomery, G.W., Pennell, C.E., Cumberland, P.M., Cotlarciuc, I., Mitchell, P., Wang, J.J., Schache, M., Janmahasathian, S., Igo Jr., R.P., Lass, J.H., Chew, E., Iyengar, S.K., Gorgels, T.G.M.F., Rudan, I., Hayward, C., Wright, A.F., Polasek, O., Vatavuk, Z., Wilson, J.F., Fleck, B., Zeller, T., Mirshahi, A., Müller, C., Uitterlinden, A.G., Rivadeneira, F., Vingerling, J.R., Hofman, A., Oostra, B.A., Amin, N., Bergen, A.A.B., Teo, Y.-Y., Rahi, J.S., Vitart, V., Williams, C., Baird, P.N., Wong, T.-Y., Oexle, K., Pfeiffer, N., Mackey, D.A., Young, T.L., Van Duijn, C.M., Saw, S.-M., Bailey-Wilson, J.E., Stambolian, D., Klaver, C.C., Hammond, C.J.
Published 2014

Multi-trait genome-wide association study identifies new loci associated with optic disc parameters

by Bonnemaijer, P.W.M., Leeuwen, E.M., Iglesias, A.I., Gharahkhani, P., Vitart, V., Khawaja, A.P., Simcoe, M., Höhn, R., Cree, A.J., Igo, R.P., Burdon, K.P., Craig, J.E., Hewitt, A.W., Jonas, J., Khor, C.-C., Pasutto, F., Mackey, D.A., Mitchell, P., Mishra, A., Pang, C., Pasquale, L.R., Springelkamp, H., Thorleifsson, G., Thorsteinsdottir, U., Viswanathan, A.C., Wojciechowski, R., Wong, T., Young, T.L., Zeller, T., Allingham, R., Budenz, D., Bailey, J.C., Fingert, J., Gaasterland, D., Gaasterland, T., Haines, J.L., Hark, L., Hauser, M., Kang, J.H., Kraft, P., Lee, R., Lichter, P., Liu, Y., Moroi, S., Pericak, M., Realini, A., Rhee, D., Richards, J.R., Ritch, R., Scott, W.K., Singh, K., Sit, A., Vollrath, D., Weinreb, R., Wollstein, G., Wilmer, D.Z., Atan, D., Aslam, T., Barman, S.A., Barrett, J.H., Bishop, P., Blows, P., Bunce, C., Carare, R.O., Chakravarthy, U., Chan, M., Chua, S.Y.L., Crabb, D.P., Cumberland, P.M., Day, A., Desai, P., Dhillon, B., Dick, A.D., Egan, C., Ennis, S., Foster, P., Fruttiger, M., Gallacher, J.E.J., Garway, D.F., Gibson, J., Gore, D., Guggenheim, J.A., Hardcastle, A., Harding, S.P., Hogg, R.E., Keane, P.A., Khaw, P.T., Lascaratos, G., Macgillivray, T., Mackie, S., Martin, K., McGaughey, M., McGuinness, B., McKay, G.J., McKibbin, M., Mitry, D., Moore, T., Morgan, J.E., Muthy, Z.A., O’Sullivan, E., Owen, C.G., Patel, P., Paterson, E., Peto, T., Petzold, A., Rahi, J.S., Rudnikca, A.R., Self, J., Sivaprasad, S., Steel, D., Stratton, I., Strouthidis, N., Sudlow, C., Thomas, D., Trucco, E., Tufail, A., Vernon, S.A., Williams, C., Williams, K., Woodside, J.V., Yates, M.M., Yip, J., Zheng, Y., Gerhold-Ay, A., Nickels, S., Wilson, J.F., Hayward, C., Boutin, T.S., Polašek, O., Aung, T., Amin, N., Lotery, A.J., Wiggs, J.L., Cheng, C.-Y., Hysi, P.G., Hammond, C.J., Thiadens, A.A.H.J., MacGregor, S., Klaver, C.C.W., Duijn, C.M., International Glaucoma Genetics Consortium., NEIGHBORHOOD consortium., UK Biobank Eye and Vision Consortium.
Published 2021

Genome-wide association study for refractive astigmatism reveals genetic co-determination with spherical equivalent refractive error: the CREAM consortium

by Li Q., Wojciechowski R., Simpson C.L., Hysi P.G., Verhoeven V.J.M., Ikram M.K., Höhn R., Vitart V., Hewitt A.W., Oexle K., Mäkelä K.-M., Ho D.W.H., Chew E., Mihailov E., Smith G.D., Biino G., Rudan I., Seppala I., Kaprio J., Craig J.E., Polling J.R., MacGregor S., Tideman J.-W., Fondran J.R., Wang J.J., Liao J., Zhao J.H., Xie J., Bailey Wilson J.E., Burdon K.P., Khaw K.-T., Yamashiro K., Pirastu M., Portas L., Farrer L., Raffel L.J., Chen L.J., Xu L., Deangelis M.M., Morrison M., Schache M., Cotch M.-F., Miyake M., Fan Q., Fossarello M., He M., Yoshimura N., Wareham N.J., Mizuki N., Pfeiffer N., Polasek O., Tam P.O., Foster P.J., Chen P., Cheng C.-Y., Gharahkhani P., Fogarty R.D., Luben R.N., Igo R.P., Jr., Klein R., Mohsen Hosseini S., Janmahasatian S., Feng S., Panda-Jonas S., St Pourcain B., Iyengar S.K., Lass J.H., Rantanen T., Haller T., Nangia V., Jhanji V., Chen W., Zhou X., Guo X., Li X., McMahon G., Vatavuk Z., The CREAM consortium, Kemp J.P., Northstone K., Rahi J.S., Cumberland P.M., Martin N.G., Sanfilippo P.G., Lu Y., Wang Y.X., Hayward C., Polašek O., Campbell H., Bencic G., Wright A.F., Wedenoja J., Zeller T., Schillert A., Mirshahi A., Lackner K., Yip S.P., Yap M.K.H., Ried J.S., Gieger C., Murgia F., Wilson J.F., Fleck B., Yazar S., Vingerling J.R., Hofman A., Uitterlinden A., Rivadeneira F., Amin N., Karssen L., Oostra B.A., Zhou X., Teo Y.-Y., Tai E.S., Vithana E., Barathi V., Zheng Y., Siantar R.G., Neelam K., Shin Y., Lam J., Yonova-Doing E., Venturini C., Hosseini S.M., Wong H.-S., Lehtimäki T., Kähönen M., Raitakari O., Timpson N.J., Evans D.M., Khor C.-C., Aung T., Young T.L., Mitchell P., Klein B., van Duijn C.M., Meitinger T., Jonas J.B., Baird P.N., Mackey D.A., Wong T.Y., Saw S.-M., Pärssinen O., Stambolian D., Hammond C.J., Klaver C.C.W., Williams C., Paterson A.D., Bailey-Wilson J.E., Guggenheim J.A., Meguro A., Young A.L., Veluchamy A.B., Metspalu A., Döring A., Khawaja A.P., Klein B.E., Pourcain B.S., Delcourt C., Maubaret C., Pang C.P.
Published 2020