Interleukin-13 Alters Tight Junction Proteins Expression Thereby Compromising Barrier Function and Dampens Rhinovirus Induced Immune Responses in Nasal Epithelium

by Huang, Z.-Q., Liu, J., Ong, H.H., Yuan, T., Zhou, X.-M., Wang, J., Tan, K.S., Chow, V.T., Yang, Q.-T., Shi, L., Ye, J., Wang, D.-Y.
Published 2021

Respiratory Viral Infections in Exacerbation of Chronic Airway Inflammatory Diseases: Novel Mechanisms and Insights From the Upper Airway Epithelium

by Tan, K.S., Lim, R.L., Liu, J., Ong, H.H., Tan, V.J., Lim, H.F., Chung, K.F., Adcock, I.M., Chow, V.T., Wang, D.Y.
Published 2021

Does rhinitis lead to asthma?

by Van Cauwenberge, P., Watelet, J.-B., Van Zele, T., Wang, D.-Y., Toskala, E., Durham, S., Fokkens, W.J., Lau, S., Leynaert, B., Wickman, M., Salapatas, M., Burney, P., Mullol, J.
Published 2014

Genetic analysis of an allergic rhinitis cohort reveals an intercellular epistasis between FAM134B and CD39

by Melchiotti R., Puan K.J., Andiappan A.K., Poh T.Y., Starke M., Zhuang L., Petsch K., Lai T.S., Chew F.T., Larbi A., Wang D.Y., Poidinger M., Rotzschke O.
Published 2018

Clinical Efficacy Evaluation of 1-Year Subcutaneous Immunotherapy for Artemisia sieversiana Pollen Allergic Rhinitis by Serum Metabolomics

by Shi, H.-Y., Pan, C., Ma, T.-T., Chen, Y.-L., Yan, W.-J., Liu, J.-G., Cao, M.-D., Huang, H.-D., Wang, D.-Y., Wang, X.-Y., Wei, J.-F.
Published 2021

Reduced growth and proliferation dynamics of nasal epithelial stem/progenitor cells in nasal polyps in vitro

by Yu, X.M., Li, C.W., Chao, S.S., Li, Y.Y., Yan, Y., Zhao, X.N., Yu, F.G., Liu, J., Shen, L., Pan, X.L., Shi, L., Wang, D.Y.
Published 2014

Infection of human Nasal Epithelial Cells with SARS-CoV-2 and a 382-nt deletion isolate lacking ORF8 reveals similar viral kinetics and host transcriptional profiles

by Gamage, A.M., Tan, K. S., Chan, W.O.Y., Liu, J., Tan, C.W., Ong, Y.K., Thong, M., Andiappan, A.K., Anderson, D.E., Wang, D.Y., Wang, L.-F.
Published 2021

Allergic rhinitis and its impact on asthma update (ARIA 2008) - western and Asian-Pacific perspective

by Pawankar, R., Bunnag, C., Chen, Y., Fukuda, T., Kim, Y.-Y., Le, L.T.T., le Huong, T.T., O'Hehir, R.E., Ohta, K., Vichyanond, P., Wang, D.-Y., Zhong, N., Khaltaev, N., Bousquet, J.
Published 2015

Aberrant localization of FOXJ1 correlates with the disease severity and comorbidities in patients with nasal polyps 11 Medical and Health Sciences 1102 Cardiorespiratory Medicine a...

by Peng, Y., Guan, W.-J., Tan, K.S., Zhu, Z., Chen, Z., Hong, H., Wang, Z., Tian, T., Zi, X., Ong, Y.K., Thong, M., Shi, L., Yang, Q., Qiu, Q., Wang, D.-Y.
Published 2021

Leukotriene A4 Hydrolase Is a Candidate Predictive Biomarker for Successful Allergen Immunotherapy

by Ma, T.-T., Cao, M.-D., Yu, R.-L., Shi, H.-Y., Yan, W.-J., Liu, J.-G., Pan, C., Sun, J., Wei, Q.-Y., Wang, D.-Y., Wei, J.-F., Wang, X.-Y., Yin, J.-S.
Published 2021

Hypoxia-inducible TAp73 supports tumorigenesis by regulating the angiogenic transcriptome

by Dulloo I., Phang B.H., Othman R., Tan S.Y., Vijayaraghavan A., Goh L.K., Martin-Lopez M., Marques M.M., Li C.W., Wang D.Y., Marin M.C., Xian W., Mckeon F., Sabapathy K.
Published 2016

Validation of GWAS loci for atopic dermatitis in a Singapore chinese population

by Andiappan, A.K., Foo, J.N., Choy, M.W., Chen, H., Common, J.E.A., Tang, M.B.Y., Van Bever, H.P., Giam, Y.C., Suri, B.K., Ramani, A., Nilkanth, P.P., Lane, E.B., Wang, D.Y., Chew, F.T., Liu, J.
Published 2014

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

by Andiappan, A.K, Melchiotti, R, Poh, T.Y, Nah, M, Puan, K.J, Vigano, E, Haase, D, Yusof, N, San Luis, B, Lum, J, Kumar, D, Foo, S, Zhuang, L, Vasudev, A, Irwanto, A, Lee, B, Nardin, A, Liu, H, Zhang, F, Connolly, J, Liu, J, Mortellaro, A, Wang, D.Y, Poidinger, M, Larbi, A, Zolezzi, F, Rotzschke, O
Published 2020

A functional SNP associated with atopic dermatitis controls cell type-specific methylation of the VSTM1 gene locus

by Kumar D., Puan K.J., Andiappan A.K., Lee B., Westerlaken G.H.A., Haase D., Melchiotti R., Li Z., Yusof N., Lum J., Koh G., Foo S., Yeong J., Alves A.C., Pekkanen J., Sun L.D., Irwanto A., Fairfax B.P., Naranbhai V., Common J.E.A., Tang M., Chuang C.K., Jarvelin M.-R., Knight J.C., Zhang X., Chew F.T., Prabhakar S., Jianjun L., Wang D.Y., Zolezzi F., Poidinger M., Lane E.B., Meyaard L., Rötzschke O.
Published 2020

Pharmacologic and anti-IgE treatment of allergic rhinitis ARIA update (in collaboration with GA2LEN)

by Bousquet, J., Van Cauwenberge, P., Aït Khaled, N., Bachert, C., Baena-Cagnani, C.E., Bouchard, J., Bunnag, C., Canonica, G.W., Carlsen, K.-H., Chen, Y.-Z., Cruz, A.A., Custovic, A., Demoly, P., Dubakiene, R., Durham, S., Fokkens, W., Howarth, P., Kemp, J., Kowalski, M.L., Kvedariene, V., Lipworth, B., Lockey, R., Lund, V., Mavale-Manuel, S., Meltzer, E.O., Mullol, J., Naclerio, R., Nekam, K., Ohta, K., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T., Potter, P., Price, D., Scadding, G., Simons, F.E.R., Spicak, V., Valovirta, E., Wang, D.-Y., Yawn, B., Yusuf, O.
Published 2016

Common variants at 9p21 and 8q22 are associated with increased susceptibility to optic nerve degeneration in glaucoma

by Wiggs J.L., Yaspan B.L., Hauser M.A., Kang J.H., Allingham R.R., Olson L.M., Abdrabou W., Fan B.J., Wang D.Y., Brodeur W., Budenz D.L., Caprioli J., Crenshaw A., Crooks K., DelBono E., Doheny K.F., Friedman D.S., Gaasterland D., Gaasterland T., Laurie C., Lee R.K., Lichter P.R., Loomis S., Liu Y., Medeiros F.A., McCarty C., Mirel D., Moroi S.E., Musch D.C., Realini A., Rozsa F.W., Schuman J.S., Scott K., Singh K., Stein J.D., Trager E.H., VanVeldhuisen P., Vollrath D., Wollstein G., Yoneyama S., Zhang K., Weinreb R.N., Ernst J., Kellis M., Masuda T., Zack D., Richards J.E., Pericak-Vance M., Pasquale L.R., Haines J.L.
Published 2019

Cell Specific eQTL Analysis without Sorting Cells

by Westra H.-J., Arends D., Esko T., Peters M.J., Schurmann C., Schramm K., Kettunen J., Yaghootkar H., Fairfax B.P., Andiappan A.K., Li Y., Fu J., Karjalainen J., Platteel M., Visschedijk M., Weersma R.K., Kasela S., Milani L., Tserel L., Peterson P., Reinmaa E., Hofman A., Uitterlinden A.G., Rivadeneira F., Homuth G., Petersmann A., Lorbeer R., Prokisch H., Meitinger T., Herder C., Roden M., Grallert H., Ripatti S., Perola M., Wood A.R., Melzer D., Ferrucci L., Singleton A.B., Hernandez D.G., Knight J.C., Melchiotti R., Lee B., Poidinger M., Zolezzi F., Larbi A., Wang D.Y., van den Berg L.H., Veldink J.H., Rotzschke O., Makino S., Salomaa V., Strauch K., Völker U., van Meurs J.B.J., Metspalu A., Wijmenga C., Jansen R.C., Franke L.
Published 2020

Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)

by Bousquet, J., Khaltaev, N., Cruz, A.A., Denburg, J., Fokkens, W.J., Togias, A., Zuberbier, T., Baena-Cagnani, C.E., Canonica, G.W., Van Weel, C., Agache, I., Aït-Khaled, N., Bachert, C., Blaiss, M.S., Bonini, S., Boulet, L.-P., Bousquet, P.-J., Camargos, P., Carlsen, K.-H., Chen, Y., Custovic, A., Dahl, R., Demoly, P., Douagui, H., Durham, S.R., Van Wijk, R.G., Kalayci, O., Kaliner, M.A., Kim, Y.-Y., Kowalski, M.L., Kuna, P., Le, L.T.T., Lemiere, C., Li, J., Lockey, R.F., Mavale-Manuel, S., Meltzer, E.O., Mohammad, Y., Mullol, J., Naclerio, R., O'Hehir, R.E., Ohta, K., Ouedraogo, S., Palkonen, S., Papadopoulos, N., Passalacqua, G., Pawankar, R., Popov, T.A., Rabe, K.F., Rosado-Pinto, J., Scadding, G.K., Simons, F.E.R., Toskala, E., Valovirta, E., Van Cauwenberge, P., Wang, D.-Y., Wickman, M., Yawn, B.P., Yorgancioglu, A., Yusuf, O.M., Zar, H., Annesi-Maesano, I., Bateman, E.D., Kheder, A.B., Boakye, D.A., Bouchard, J., Burney, P., Busse, W.W., Chan-Yeung, M., Chavannes, N.H., Chuchalin, A., Dolen, W.K., Emuzyte, R., Grouse, L., Humbert, M., Jackson, C., Johnston, S.L., Keith, P.K., Kemp, J.P., Klossek, J.-M., Larenas-Linnemann, D., Lipworth, B., Malo, J.-L., Marshall, G.D., Naspitz, C., Nekam, K., Niggemann, B., Nizankowska-Mogilnicka, E., Okamoto, Y., Orru, M.P., Potter, P., Price, D., Stoloff, S.W., Vandenplas, O., Viegi, G., Williams, D.
Published 2015

Breast cancer and hormone replacement therapy: Collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast...

by Calle, E.E., Heath Jr., C.W., Coates, R.J., Liff, J.M., Franceschi, S., Talamini, R., Chantarakul, N., Koetsawang, S., Rachawat, D., Morabia, A., Schuman, L., Stewart, W., Szklo, M., Bain, C., Schofield, F., Siskind, V., Band, P., Coldman, A.J., Gallagher, R.P., Hislop, T.G., Yang, P., Duffy, S.W., Kolonel, L.M., Nomura, A.M.Y., Oberle, M.W., Ory, H.W., Peterson, H.B., Wilson, H.G., Wingo, P.A., Ebeling, K., Kunde, D., Nishan, P., Colditz, G., Martin, N., Pardthaisong, T., Silpisornkosol, S., Theetranont, C., Boosiri, B., Chutivongse, S., Jimakorn, P., Virutamasen, P., Wongsrichanalai, C., McMichael, A.J., Rohan, T., Ewertz, M., Paul, C., Skegg, D.C.G., Spears, G.F.S., Boyle, P., Evstifeeva, M., Daling, J.R., Hutchinson, W.B., Malone, K., Noonan, E.A., Stanford, J.L., Thomas, D.B., Weiss, N.S., White, E., Andrieu, N., Bràmond, A., Clavel, F., Gairard, B., Lansac, J., Piana, L., Renaud, R., Fine, S.R.P., Cuevas, H.R., Ontiveros, P., Palet, A., Salazar, S.B., Aristizabel, N., Cuadros, A., Bachelot, A., Lê, M.G., Deacon, J., Peto, J., Taylor, C.N., Alfandary, E., Modan, B., Ron, E., Friedman, G.D., Hiatt, R.A., Bishop, T., Kosmelj, J., Primic-Zakelj, M., Ravnihar, B., Stare, J., Beeson, W.L., Fraser, G., Bulbrook, R.D., Cuzick, J., Fentiman, I.S., Hayward, J.L., Wang, D.Y., Hanson, R.L., Leske, M.C., Mahoney, M.C., Nasca, P.C., Varma, A.O., Weinstein, A.L., Moller, T.R., Olsson, H., Ranstam, J., Goldbohm, R.A., van den Brandt, P.A., Apelo, R.A., Baens, J., de la Cruz, J.R., Javier, B., Lacaya, L.B., Ngelangel, C.A., La Vecchia, C., Negri, E., Marubini, E., Ferraroni, M., Gerber, M., Richardson, S., Segala, C., Gatei, D., Kenya, P., Kungu, A., Mati, J.G., Brinton, L.A., Hoover, R., Schairer, C., Spirtas, R., Lee, H.P., Rookus, M.A., van Leeuwen, F.E., Schoenberg, J.A., Gammon, M.D., Clarke, E.A., Jones, L., McPherson, K., Neil, A., Vessey, M., Yeates, D., Beral, V., Bull, D., Crossley, B., Hermon, C., Jones, S., Key, T., Lewis, C., Reeves, G., Collins, R., Doll, R., Peto, R., Hannaford, P., Kay, C., Rosero-Bixby, L., Yuan, J.-M., Wei, H.Y., Yun, T., Zhiheng, C., Berry, G., Cooper Booth, J., Jelihovsky, T., MacLennan, R., Shearman, R., Wang, Q.-S., Baines, C.J., Miller, A.B., Wall, C., Lund, E., Stalsberg, H., Dabancens, A., Martinez, L., Molina, R., Salas, O., Alexander, F.E., Hulka, B.S., Chilvers, C.E.D., Bernstein, L., Haile, R.W., Paganini-Hill, A., Pike, M.C., Ross, R.K., Ursin, G., Yu, M.C., Longnecker, M.P., Newcomb, P., Farley, T.M.N., Holck, S., Meirik, O., Adami, H.O., Bergkvist, R., Persson, I., Levi, F., McPherson, K., Mabuchi, K., Preston, D., Katsouyanni, K., Trichopoulou, A., Trichopoulos, D., Bergkvist, L.
Published 2016

Next-generation ARIA care pathways for rhinitis and asthma: A model for multimorbid chronic diseases

by Bousquet, J.J., Schünemann, H.J., Togias, A., Erhola, M., Hellings, P.W., Zuberbier, T., Agache, I., Ansotegui, I.J., Anto, J.M., Bachert, C., Becker, S., Bedolla-Barajas, M., Bewick, M., Bosnic-Anticevich, S., Bosse, I., Boulet, L.P., Bourrez, J.M., Brusselle, G., Chavannes, N., Costa, E., Cruz, A.A., Czarlewski, W., Fokkens, W.J., Fonseca, J.A., Gaga, M., Haahtela, T., Illario, M., Klimek, L., Kuna, P., Kvedariene, V., Le, L.T.T., Larenas-Linnemann, D., Laune, D., Lourenço, O.M., Menditto, E., Mullol, J., Okamoto, Y., Papadopoulos, N., Pham-Thi, N., Picard, R., Pinnock, H., Roche, N., Roller-Wirnsberger, R.E., Rolland, C., Samolinski, B., Sheikh, A., Toppila-Salmi, S., Tsiligianni, I., Valiulis, A., Valovirta, E., Vasankari, T., Ventura, M.-T., Walker, S., Williams, S., Akdis, C.A., Annesi-Maesano, I., Arnavielhe, S., Basagana, X., Bateman, E., Bedbrook, A., Bennoor, K.S., Benveniste, S., Bergmann, K.C., Bialek, S., Billo, N., Bindslev-Jensen, C., Bjermer, L., Blain, H., Bonini, M., Bonniaud, P., Bouchard, J., Briedis, V., Brightling, C.E., Brozek, J., Buhl, R., Buonaiuto, R., Canonica, G.W., Cardona, V., Carriazo, A.M., Carr, W., Cartier, C., Casale, T., Cecchi, L., Cepeda Sarabia, A.M., Chkhartishvili, E., Chu, D.K., Cingi, C., Colgan, E., De Sousa, J.C., Courbis, A.L., Custovic, A., Cvetkosvki, B., Damato, G., Da Silva, J., Dantas, C., Dokic, D., Dauvilliers, Y., Dedeu, A., De Feo, G., Devillier, P., Di Capua, S., Dykewickz, M., Dubakiene, R., Ebisawa, M., El-Gamal, Y., Eller, E., Emuzyte, R., Farrell, J., Fink-Wagner, A., Fiocchi, A., Fontaine, J.F., Gemicio?lu, B., Schmid-Grendelmeir, P., Gamkrelidze, A., Garcia-Aymerich, J., Gomez, M., Diaz, S.G., Gotua, M., Guldemond, N.A., Guzmán, M.-A., Hajjam, J., O'Hourihane, J.B., Humbert, M., Service de Pneumologie, Hôpital Bicêtre, Inserm UMR-S999, Le Kremlin Bicêtre, France., Iaccarino, G., Ierodiakonou, D., Ivancevich, J.C., Joos, G., Jung, K.-S., Jutel, M., Kaidashev, I., Kalayci, O., Kardas, P., Keil, T., Khaitov, M., Khaltaev, N., Kleine-Tebbe, J., Kowalski, M.L., Kritikos, V., Kull, I., Leonardini, L., Lieberman, P., Lipworth, B., Lodrup Carlsen, K.C., Loureiro, C.C., Louis, R., Mair, A., Marien, G., Mahboub, B., Malva, J., Manning, P., De Manuel Keenoy, E., Marshall, G.D., Masjedi, M.R., Maspero, J.F., Mathieu-Dupas, E., Matricardi, P.M., Melén, E., Melo-Gomes, E., Meltzer, E.O., Mercier, J., Miculinic, N., Mihaltan, F., Milenkovic, B., Moda, G., Mogica-Martinez, M.-D., Mohammad, Y., Montefort, S., Monti, R., Morais-Almeida, M., Mösges, R., Münter, L., Muraro, A., Murray, R., Naclerio, R., Napoli, L., Namazova-Baranova, L., Neffen, H., Nekam, K., Neou, A., Novellino, E., Nyembue, D., O'Hehir, R., Ohta, K., Okubo, K., Onorato, G., Ouedraogo, S., Pali-Schöll, I., Palkonen, S., Panzner, P., Park, H.-S., Pépin, J.-L., Pereira, A.-M., Pfaar, O., Paulino, E., Phillips, J., Plavec, D., Popov, T.A., Portejoie, F., Price, D., Prokopakis, E.P., Pugin, B., Raciborski, F., Rajabian-Söderlund, R., Reitsma, S., Rodo, X., Romano, A., Rosario, N., Rottem, M., Ryan, D., Salimäki, J., Sanchez-Borges, M.M., Sisul, J.-C., Solé, D., Somekh, D., Sooronbaev, T., Sova, M., Spranger, O., Stellato, C., Stelmach, R., Ulrik, C.S., Thibaudon, M., To, T., Todo-Bom, A., Tomazic, P.V., Valero, A.A., Valenta, R., Valentin-Rostan, M., Van Der Kleij, R., Vandenplas, O., Vezzani, G., Viart, F., Viegi, G., Wallace, D., Wagenmann, M., Wang, D.Y., Waserman, S., Wickman, M., Williams, D.M., Wong, G., Wroczynski, P., Yiallouros, P.K., Yorgancioglu, A., Yusuf, O.M., Zar, H.J., Zeng, S., Zernotti, M., Zhang, L., Zhong, N.S., Zidarn, M.
Published 2021