Continuous time Bayesian networks identify Prdm1 as a negative regulator of TH17 cell differentiation in humans

by Acerbi, E, Viganò, E, Poidinger, M, Mortellaro, A, Zelante, T, Stella, F
Published 2020

Mechanical interactions between dendritic cells and T cells correlate with T cell responsiveness

by Lim, T.S., Mortellaro, A., Lim, C.T., Hämmerling, G.J., Ricciardi-Castagnoli, P.
Published 2014

CD80 and CD86 Differentially Regulate Mechanical Interactions of T-Cells with Antigen-Presenting Dendritic Cells and B-Cells

by Lim, T.S., Goh, J.K.H., Mortellaro, A., Lim, C.T., Hämmerling, G.J., Ricciardi-Castagnoli, P.
Published 2014

Inhibition of NLRP3 inflammasome activation by cell-permeable stapled peptides

by Pal, A., Neo, K., Rajamani, L., Ferrer, F.J., Lane, D.P., Verma, C.S., Mortellaro, A.
Published 2021

Calcineurin B in CD4+ T Cells prevents autoimmune colitis by negatively regulating the JAK/STAT pathway

by Mencarelli, A, Vacca, M, Khameneh, H.J, Acerbi, E, Tay, A, Zolezzi, F, Poidinger, M, Mortellaro, A
Published 2020

C5a regulates IL-1β production and leukocyte recruitment in a murine model of monosodium urate crystal-induced peritonitis

by Khameneh, H.J, Ho, A.W.S, Laudisi, F, Derks, H, Kandasamy, M, Sivasankar, B, Teng, G.G, Mortellaro, A
Published 2020

The inflammasome adaptor ASC intrinsically limits CD4+ T-cell proliferation to help maintain intestinal homeostasis

by Khameneh, H.J., Leong, K.W.K., Mencarelli, A., Vacca, M., Mambwe, B., Neo, K., Tay, A., Zolezzi, F., Lee, B., Mortellaro, A.
Published 2021

Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages

by Tailleux L., Waddel S.J., Pelizzola M., Mortellaro A., Withers M., Tanne A., Castagnoli P.R., Gicquel B., Stoker N.G., Butcher P.D., Foti M., Neyrolles O.
Published 2020

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

by Mencarelli A., Khameneh H.J., Fric J., Vacca M., El Daker S., Janela B., Tang J.P., Nabti S., Balachander A., Lim T.S., Ginhoux F., Ricciardi-Castagnoli P., Mortellaro A.
Published 2020

Nod2 is required for the early innate immune clearance of Acinetobacter baumannii from the lungs

by Kale S.D., Dikshit N., Kumar P., Balamuralidhar V., Khameneh H.J., Bin Abdul Malik N., Koh T.H., Tan G.G.Y., Tan T.T., Mortellaro A., Sukumaran B.
Published 2020

The NLRP3 Inflammasome May Contribute to Pathologic Neovascularization in the Advanced Stages of Diabetic Retinopathy

by Chaurasia, S.S, Lim, R.R, Parikh, B.H, Wey, Y.S, Tun, B.B, Wong, T.Y, Luu, C.D, Agrawal, R, Ghosh, A, Mortellaro, A, Rackoczy, E, Mohan, R.R, Barathi, V.A
Published 2020

NLRP10 enhances CD4+ T-cell-mediated IFN? response via regulation of dendritic cell-derived IL-12 release

by Vacca, M, Böhme, J, Zambetti, L.P, Khameneh, H.J, Paleja, B.S, Laudisi, F, Ho, A.W.S, Neo, K, Leong, K.W.K, Marzuki, M, Lee, B, Poidinger, M, Santambrogio, L, Tsenova, L, Zolezzi, F, de Libero, G, Singhal, A, Mortellaro, A
Published 2020

E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP

by Bist P., Cheong W.S., Ng A., Dikshit N., Kim B.-H., Pulloor N.K., Khameneh H.J., Hedl M., Shenoy A.R., Balamuralidhar V., Malik N.B.A., Hong M., Neutzner A., Chin K.-C., Kobayashi K.S., Bertoletti A., Mortellaro A., Abraham C., MacMicking J.D., Xavier R.J., Sukumaran B.
Published 2020

Erratum: E3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP

by Bist, P., Cheong, W.S., Ng, A., Dikshit, N., Kim, B.H., Pulloor, N.K., Khameneh, H.J., Hedl, M., Shenoy, A.R., Balamuralidhar, V., Malik, N.B.A., Hong, M., Neutzner, A., Chin, K.-C., Kobayashi, K.S., Bertoletti, A., Mortellaro, A., Abraham, C., MacMicking, J.D., Xavier, R.J., Sukumaran, B.
Published 2020

Genome-wide analysis of the genetic regulation of gene expression in human neutrophils

by Andiappan, A.K, Melchiotti, R, Poh, T.Y, Nah, M, Puan, K.J, Vigano, E, Haase, D, Yusof, N, San Luis, B, Lum, J, Kumar, D, Foo, S, Zhuang, L, Vasudev, A, Irwanto, A, Lee, B, Nardin, A, Liu, H, Zhang, F, Connolly, J, Liu, J, Mortellaro, A, Wang, D.Y, Poidinger, M, Larbi, A, Zolezzi, F, Rotzschke, O
Published 2020