Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia

by Kam, Y.-W., Ahmed, M.Y., Amrun, S.N., Lee, B., Refaie, T., Elgizouli, K., Fong, S.-W., Renia, L., Ng, L.F.P.
Published 2021

Virus infection drives IL-2 antibody complexes into pro-inflammatory agonists in mice

by Lee, W.W.L, Teo, T.-H, Lum, F.-M, Andiappan, A.K, Amrun, S.N, Rénia, L, Rötzschke, O, Ng, L.F.P
Published 2020

TREM-1 activation is a potential key regulator in driving severe pathogenesis of enterovirus A71 infection

by Amrun, S.N., Tan, J.J.L., Rickett, N.Y., Cox, J.A., Lee, B., Griffiths, M.J., Solomon, T., Perera, D., Ooi, M.H., Hiscox, J.A., Ng, L.F.P.
Published 2021

Novel differential linear B-cell epitopes to identify Zika and dengue virus infections in patients

by Amrun, S.N., Yee, W.-X., Abu Bakar, F., Lee, B., Kam, Y.-W., Lum, F.-M., Tan, J.J.L., Lim, V.W.X., Watthanaworawit, W., Ling, C., Nosten, F., Renia, L., Leo, Y.-S., Ng, L.F.P.
Published 2021

Plasmodium co-infection protects against chikungunya virus-induced pathologies

by Teo, T.-H, Lum, F.-M, Ghaffar, K, Chan, Y.-H, Amrun, S.N, Tan, J.J.L, Lee, C.Y.P, Chua, T.-K, Carissimo, G, Lee, W.W.L, Claser, C, Rajarethinam, R, Rénia, L, Ng, L.F.P
Published 2020

Mutating chikungunya virus non-structural protein produces potent live-attenuated vaccine candidate

by Chan, Y.-H., Teo, T.-H., Utt, A., Tan, J.J.L., Amrun, S.N., Abu Bakar, F., Yee, W.-X., Becht, E., Lee, C.Y.-P., Lee, B., Rajarethinam, R., Newell, E., Merits, A., Carissimo, G., Lum, F.-M., Ng, L.F.P.
Published 2021

Sensitive detection of total anti-Spike antibodies and isotype switching in asymptomatic and symptomatic individuals with COVID-19

by Goh, YS, Chavatte, JM, Lim Jieling, A, Lee, B, Hor, PX, Amrun, SN, Lee, CYP, Chee, RSL, Wang, B, Lee, CY, Ngoh, EZX, Wang, CI, Young, BE, Tambyah, PA, Kalimuddin, S, Pada, S, Tan, SY, Sun, LJ, Chen, MIC, Leo, YS, Lye, DC, Ng, LFP, Lin, RTP, Renia, L
Published 2021

Multimodal assessments of Zika virus immune pathophysiological responses in marmosets

by Lum, F.-M, Zhang, W, Lim, K.-C, Malleret, B, Teo, T.-H, Koh, J.-J, Lee, K.J, Chua, T.-K, Kam, Y.-W, Yee, W.-X, Huen, I, Tan, J.J.L, Amrun, S.N, Prakash KN, B, Cozzone, P.J, Renia, L, Lee, P.T.H, Ng, L.F.P
Published 2020

Cross-reactive dengue human monoclonal antibody prevents severe pathologies and death from Zika virus infections

by Kam, Y.-W, Lee, C.Y.-P, Teo, T.-H, Howland, S.W, Amrun, S.N, Lum, F.-M, See, P, Kng, N.Q.-R, Huber, R.G, Xu, M.-H, Tan, H.-L, Choo, A, Maurer-Stroh, S, Ginhoux, F, Fink, K, Wang, C.-I, Ng, L.F, R‚nia, L
Published 2020

Immunological observations and transcriptomic analysis of trimester-specific full-term placentas from three Zika virus-infected women

by Lum, F.-M., Narang, V., Hue, S., Chen, J., McGovern, N., Rajarethinam, R., Tan, J.J.L., Amrun, S.N., Chan, Y.-H., Lee, C.Y.P., Chua, T.-K., Yee, W.-X., Yeo, N.K.W., Tan, T.-C., Liu, X., Haldenby, S., Leo, Y.-S., Ginhoux, F., Chan, J.K.Y., Hiscox, J., Chong, C.-Y., Ng, L.F.P.
Published 2021

Whole blood immunophenotyping uncovers immature neutrophil-to-VD2 T-cell ratio as an early marker for severe COVID-19

by Carissimo, G., Xu, W., Kwok, I., Abdad, M.Y., Chan, Y.-H., Fong, S.-W., Puan, K.J., Lee, C.Y.-P., Yeo, N.K.-W., Amrun, S.N., Chee, R.S.-L., How, W., Chan, S., Fan, B.E., Andiappan, A.K., Lee, B., Rötzschke, O., Young, B.E., Leo, Y.-S., Lye, D.C., Renia, L., Ng, L.G., Larbi, A., Ng, L.F.
Published 2021

Two linear epitopes on the SARS-CoV-2 spike protein that elicit neutralising antibodies in COVID-19 patients

by Poh, C.M., Carissimo, G., Wang, B., Amrun, S.N., Lee, C.Y.-P., Chee, R.S.-L., Fong, S.-W., Yeo, N.K.-W., Lee, W.-H., Torres-Ruesta, A., Leo, Y.-S., Chen, M.I.-C., Tan, S.-Y., Chai, L.Y.A., Kalimuddin, S., Kheng, S.S.G., Thien, S.-Y., Young, B.E., Lye, D.C., Hanson, B.J., Wang, C.-I., Renia, L., Ng, L.F.P.
Published 2021

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity

by Amrun, S.N., Lee, C.Y.-P., Lee, B., Fong, S.-W., Young, B.E., Chee, R.S.-L., Yeo, N.K.-W., Torres-Ruesta, A., Carissimo, G., Poh, C.M., Chang, Z.W., Tay, M.Z., Chan, Y.-H., Chen, M.I.-C., Low, J.G.-H., Tambyah, P.A., Kalimuddin, S., Pada, S., Tan, S.-Y., Sun, L.J., Leo, Y.-S., Lye, D.C., Renia, L., Ng, L.F.P.
Published 2021