A novel F420-dependent anti-oxidant mechanism protects Mycobacterium tuberculosis against oxidative stress and bactericidal agents

by Gurumurthy, M., Rao, M., Mukherjee, T., Rao, S.P.S., Boshoff, H.I., Dick, T., Barry, C.E., Manjunatha, U.H.
Published 2014

Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression

by Park S., Klotzsche M., Wilson D.J., Boshoff H.I., Eoh H., Manjunatha U., Blumenthal A., Rhee K., Barry C.E., Aldrich C.C., Ehrt S., Schnappinger D.
Published 2019

Substrate specificity of the deazaflavin-dependent nitroreductase from Mycobacterium tuberculosis responsible for the bioreductive activation of bicyclic nitroimidazoles

by Gurumurthy, M., Mukherjee, T., Dowd, C.S., Singh, R., Niyomrattanakit, P., Tay, J.A., Nayyar, A., Lee, Y.S., Cherian, J., Boshoff, H.I., Dick, T., Barry III, C.E., Manjunatha, U.H.
Published 2014

Exploring the Mode of Action of Bioactive Compounds by Microfluidic Transcriptional Profiling in Mycobacteria

by Murima, P., de Sessions, P.F., Lim, V., Naim, A.N.M., Bifani, P., Boshoff, H.I.M., Sambandamurthy, V.K., Dick, T., Hibberd, M.L., Schreiber, M., Rao, S.P.S.
Published 2014

Pharmacokinetics-pharmacodynamics analysis of bicyclic 4-nitroimidazole analogs in a murine model of tuberculosis

by Lakshminarayana S.B., Boshoff H.I.M., Cherian J., Ravindran S., Goh A., Jiricek J., Nanjundappa M., Nayyar A., Gurumurthy M., Singh R., Dick T., Blasco F., Barry III C.E., Ho P.C., Manjunatha U.H.
Published 2018

A high-throughput screen to identify inhibitors of ATP homeostasis in non-replicating mycobacterium tuberculosis

by Mak, P.A., Rao, S.P.S., Ping Tan, M., Lin, X., Chyba, J., Tay, J., Ng, S.H., Tan, B.H., Cherian, J., Duraiswamy, J., Bifani, P., Lim, V., Lee, B.H., Ling Ma, N., Beer, D., Thayalan, P., Kuhen, K., Chatterjee, A., Supek, F., Glynne, R., Zheng, J., Boshoff, H.I., Barry, C.E., Dick T., Pethe, K., Camacho, L.R.
Published 2014