Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression

10.1371/journal.ppat.1002264

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Bibliographic Details
Main Authors:	Park S., Klotzsche M., Wilson D.J., Boshoff H.I., Eoh H., Manjunatha U., Blumenthal A., Rhee K., Barry C.E., Aldrich C.C., Ehrt S., Schnappinger D.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2019
Subjects:	7,8 diaminopelargonic acid synthase anhydrotetracycline biotin biotin derivative doxycycline unclassified drug aminotransferase bacterial protein BioA protein, bacteria animal experiment animal model animal tissue article bacterial growth bacterial viability biotinylation controlled study enzyme activity gene expression regulation gene silencing in vitro study in vivo study mouse Mycobacterium tuberculosis nonhuman protein synthesis quantitative analysis sensitivity analysis signal transduction tuberculosis wild type animal biosynthesis chronic disease disease model drug delivery system enzymology genetics metabolism methodology mutation Bacteria (microorganisms) Murinae Mus Animals Bacterial Proteins Biotin Chronic Disease Disease Models, Animal Drug Delivery Systems Mice Mutation Transaminases Tuberculosis
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161652
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Institution:	National University of Singapore

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