Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression

10.1371/journal.ppat.1002264

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Main Authors:	Park S., Klotzsche M., Wilson D.J., Boshoff H.I., Eoh H., Manjunatha U., Blumenthal A., Rhee K., Barry C.E., Aldrich C.C., Ehrt S., Schnappinger D.
Other Authors:	MICROBIOLOGY AND IMMUNOLOGY
Format:	Article
Published:	2019
Subjects:	7,8 diaminopelargonic acid synthase anhydrotetracycline biotin biotin derivative doxycycline unclassified drug aminotransferase bacterial protein BioA protein, bacteria animal experiment animal model animal tissue article bacterial growth bacterial viability biotinylation controlled study enzyme activity gene expression regulation gene silencing in vitro study in vivo study mouse Mycobacterium tuberculosis nonhuman protein synthesis quantitative analysis sensitivity analysis signal transduction tuberculosis wild type animal biosynthesis chronic disease disease model drug delivery system enzymology genetics metabolism methodology mutation Bacteria (microorganisms) Murinae Mus Animals Bacterial Proteins Biotin Chronic Disease Disease Models, Animal Drug Delivery Systems Mice Mutation Transaminases Tuberculosis
Online Access:	https://scholarbank.nus.edu.sg/handle/10635/161652
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Institution:	National University of Singapore

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spelling	sg-nus-scholar.10635-1616522024-03-27T08:08:48Z Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression Park S. Klotzsche M. Wilson D.J. Boshoff H.I. Eoh H. Manjunatha U. Blumenthal A. Rhee K. Barry C.E. Aldrich C.C. Ehrt S. Schnappinger D. MICROBIOLOGY AND IMMUNOLOGY 7,8 diaminopelargonic acid synthase anhydrotetracycline biotin biotin derivative doxycycline unclassified drug aminotransferase bacterial protein BioA protein, bacteria animal experiment animal model animal tissue article bacterial growth bacterial viability biotinylation controlled study enzyme activity gene expression regulation gene silencing in vitro study in vivo study mouse Mycobacterium tuberculosis nonhuman protein synthesis quantitative analysis sensitivity analysis signal transduction tuberculosis wild type animal biosynthesis chronic disease disease model drug delivery system enzymology genetics metabolism methodology mutation tuberculosis Bacteria (microorganisms) Murinae Mus Mycobacterium tuberculosis Animals Bacterial Proteins Biotin Chronic Disease Disease Models, Animal Drug Delivery Systems Mice Mutation Mycobacterium tuberculosis Transaminases Tuberculosis 10.1371/journal.ppat.1002264 PLoS Pathogens 7 9 e1002264 2019-11-06T09:31:59Z 2019-11-06T09:31:59Z 2011 Article Park S., Klotzsche M., Wilson D.J., Boshoff H.I., Eoh H., Manjunatha U., Blumenthal A., Rhee K., Barry C.E., Aldrich C.C., Ehrt S., Schnappinger D. (2011). Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression. PLoS Pathogens 7 (9) : e1002264. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.ppat.1002264 15537366 https://scholarbank.nus.edu.sg/handle/10635/161652 Unpaywall 20191101
institution	National University of Singapore
building	NUS Library
continent	Asia
country	Singapore Singapore
content_provider	NUS Library
collection	ScholarBank@NUS
topic	7,8 diaminopelargonic acid synthase anhydrotetracycline biotin biotin derivative doxycycline unclassified drug aminotransferase bacterial protein BioA protein, bacteria animal experiment animal model animal tissue article bacterial growth bacterial viability biotinylation controlled study enzyme activity gene expression regulation gene silencing in vitro study in vivo study mouse Mycobacterium tuberculosis nonhuman protein synthesis quantitative analysis sensitivity analysis signal transduction tuberculosis wild type animal biosynthesis chronic disease disease model drug delivery system enzymology genetics metabolism methodology mutation tuberculosis Bacteria (microorganisms) Murinae Mus Mycobacterium tuberculosis Animals Bacterial Proteins Biotin Chronic Disease Disease Models, Animal Drug Delivery Systems Mice Mutation Mycobacterium tuberculosis Transaminases Tuberculosis
spellingShingle	7,8 diaminopelargonic acid synthase anhydrotetracycline biotin biotin derivative doxycycline unclassified drug aminotransferase bacterial protein BioA protein, bacteria animal experiment animal model animal tissue article bacterial growth bacterial viability biotinylation controlled study enzyme activity gene expression regulation gene silencing in vitro study in vivo study mouse Mycobacterium tuberculosis nonhuman protein synthesis quantitative analysis sensitivity analysis signal transduction tuberculosis wild type animal biosynthesis chronic disease disease model drug delivery system enzymology genetics metabolism methodology mutation tuberculosis Bacteria (microorganisms) Murinae Mus Mycobacterium tuberculosis Animals Bacterial Proteins Biotin Chronic Disease Disease Models, Animal Drug Delivery Systems Mice Mutation Mycobacterium tuberculosis Transaminases Tuberculosis Park S. Klotzsche M. Wilson D.J. Boshoff H.I. Eoh H. Manjunatha U. Blumenthal A. Rhee K. Barry C.E. Aldrich C.C. Ehrt S. Schnappinger D. Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
description	10.1371/journal.ppat.1002264
author2	MICROBIOLOGY AND IMMUNOLOGY
author_facet	MICROBIOLOGY AND IMMUNOLOGY Park S. Klotzsche M. Wilson D.J. Boshoff H.I. Eoh H. Manjunatha U. Blumenthal A. Rhee K. Barry C.E. Aldrich C.C. Ehrt S. Schnappinger D.
format	Article
author	Park S. Klotzsche M. Wilson D.J. Boshoff H.I. Eoh H. Manjunatha U. Blumenthal A. Rhee K. Barry C.E. Aldrich C.C. Ehrt S. Schnappinger D.
author_sort	Park S.
title	Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
title_short	Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
title_full	Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
title_fullStr	Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
title_full_unstemmed	Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
title_sort	evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression
publishDate	2019
url	https://scholarbank.nus.edu.sg/handle/10635/161652
_version_	1795300775817117696

Evaluating the sensitivity of mycobacterium tuberculosis to biotin deprivation using regulated gene expression

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