Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles

by Lieuwe D.J. Bos, Brendon P. Scicluna, David S.Y. Ong, Olaf Cremer, Tom Van Der Poll, Marcus J. Schultz
Published 2020

Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumonia

by Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Olaf L. Cremer, Marcus J. Schultz, Marc M.J. Bonten, Brendon P. Scicluna, Tom van der Poll
Published 2022

Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study

by Fabrice Uhel, Hessel Peters-Sengers, Fahimeh Falahi, Brendon P. Scicluna, Lonneke A. van Vught, Marc J. Bonten, Olaf L. Cremer, Marcus J. Schultz, Tom van der Poll
Published 2020

The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission

by Hina N. Khan, Aldo Jongejan, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Olaf L. Cremer, Marc J. Bonten, Tom van der Poll, Brendon P. Scicluna
Published 2022

Blood leukocyte transcriptomes in Gram-positive and Gram-negative community-acquired pneumonia

by Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Joe Butler, Lonneke A. van Vught, Katie L. Burnham, Emma E. Davenport, Julian C. Knight, Olaf L. Cremer, Marcus J. Schultz, Marc M.J. Bonten, Brendon P. Scicluna, Tom van der Poll
Published 2022

Plasma Ferritin as Marker of Macrophage Activation-Like Syndrome in Critically Ill Patients With Community-Acquired Pneumonia

by Xanthe Brands, Floris M.C. De Vries, Fabrice Uhel, Bastiaan W. Haak, Hessel Peters-Sengers, Alex R. Schuurman, Tjitske S.R. Van Engelen, René Lutter, Olaf L. Cremer, Marc J. Bonten, Marcus J. Schultz, Brendon P. Scicluna, Tom Van Der Poll
Published 2022

HIVEP1 Is a Negative Regulator of NF-κB That Inhibits Systemic Inflammation in Sepsis

by Hisatake Matsumoto, Brendon P. Scicluna, Kin Ki Jim, Fahimeh Falahi, Wanhai Qin, Berke Gürkan, Erik Malmström, Mariska T. Meijer, Joe M. Butler, Hina N. Khan, Tsuyoshi Takagi, Shunsuke Ishii, Marcus J. Schultz, Diederik van de Beek, Alex F. de Vos, Cornelis van ‘t Veer, Tom van der Poll
Published 2022

Consumptive coagulopathy is associated with a disturbed host response in patients with sepsis

by Lonneke A. van Vught, Fabrice Uhel, Chao Ding, Cees van‘t Veer, Brendon P. Scicluna, Hessel Peters-Sengers, Peter M.C. Klein Klouwenberg, Peter Nürnberg, Olaf L. Cremer, Marcus J. Schultz, Tom van der Poll, Friso M. de Beer, Lieuwe D.J. Bos, Gerie J. Glas, Arie J. Hoogendijk, Roosmarijn T.M. van Hooijdonk, Janneke Horn, Mischa A. Huson, Laura R.A. Schouten, Marleen Straat, Luuk Wieske, Maryse A. Wiewel, Esther Witteveen, Marc J.M. Bonten, Olaf M. Cremer, David S.Y. Ong, Jos F. Frencken, Maria E. Koster-Brouwer, Kirsten van de Groep, Diana M. Verboom
Published 2022

Source-specific host response and outcomes in critically ill patients with sepsis: a prospective cohort study

by Hessel Peters-Sengers, Joe M. Butler, Fabrice Uhel, Marcus J. Schultz, Marc J. Bonten, Olaf L. Cremer, Brendon P. Scicluna, Lonneke A. van Vught, Tom van der Poll, Friso M. de Beer, Lieuwe D.J. Bos, Gerie J. Glas, Roosmarijn T.M. van Hooijdonk, Janneke Horn, Laura R.A. Schouten, Marleen Straat, Luuk Wieske, Esther Witteveen, Tom D.Y. Reijnders, Alex R. Schuurman, Tjitske S.R. van Engelen, Liza Pereverzeva, Arie J. Hoogendijk, Mischa A. Huson, Maryse A. Wiewel, Peter M.C.Klein Klouwenberg, David S.Y. Ong, Jos F. Frencken, Maria E. Koster-Brouwer, Kirsten van de Groep, Diana M. Verboom
Published 2022

Patients with hypothermic sepsis have a unique gene expression profile compared to patients with fever and sepsis

by Matthew B.A. Harmon, Brendon P. Scicluna, Maryse A. Wiewel, Marcus J. Schultz, Janneke Horn, Olaf L. Cremer, Tom van der Poll, W. Joost Wiersinga, Nicole P. Juffermans, Friso M. de Beer, Lieuwe D. Bos, Gerie J. Glas, Janneke Horn, Arie J. Hoogendijk, Roosmarijn T. van Hooijdonk, Mischa A. Huson, Tom van der Poll, Brendon Scicluna, Laura R. Schouten, Marcus J. Schultz, Marleen Straat, Lonneke A. van Vught, Luuk Wieske, Esther Witteveen, Marc J. Bonten, Olaf L. Cremer, Jos F. Frencken, Kirsten van de Groep, Peter M. Klein Klouwenberg, Maria E. Koster–Brouwer, David S. Ong, Meri R. Varkila, Diana M. Verboom
Published 2022

Biological subphenotypes of acute respiratory distress syndrome show prognostic enrichment in mechanically ventilated patients without acute respiratory distress syndrome

by Nanon F.L. Heijnen, Laura A. Hagens, Marry R. Smit, Olaf L. Cremer, David S.Y. Ong, Tom Van Der Poll, Lonneke A. Van Vught, Brendon P. Scicluna, Ronny M. Schnabel, Iwan C.C. Van Der Horst, Marcus J. Schultz, Dennis C.J.J. Bergmans, Lieuwe D.J. Bos, Friso M. De Beer, Lieuwe D. Bos, Gerie J. Glas, Janneke Horn, Arie J. Hoogendijk, Roosmarijn T. Van Hooijdonk, Mischa A. Huson, Tom Van Der Poll, Laura R. Schouten, Marcus J. Schultz, Marleen Straat, Luuk Wieske, Maryse A. Wievel, Esther Witteveen, Marc J. Bonten, Jos F. Frencken, Kirsten Van De Groep, Peter M. Klein Klouwenberg, Maria E. Koster-Brouwer, Meri R. Varkila, Diana M. Verboom
Published 2022