Immunomodulation by macrolides: therapeutic potential for critical care

by Tom D.Y. Reijnders, Anno Saris, Marcus J. Schultz, Tom van der Poll
Published 2020

Host-Pathogen Interaction in Invasive Salmonellosis

by Hanna K. de Jong, Chris M. Parry, Tom van der Poll, W. Joost Wiersinga
Published 2018

Melioidosis: Insights into the pathogenicity of Burkholderia pseudomallei

by W. Joost Wiersinga, Tom van der Poll, Nicholas J. White, Nicholas P. Day, Sharon J. Peacock
Published 2018

Activation of cytotoxic lymphocytes in patients with scrub typhus

by Maaike De Fost, Wirongrong Chierakul, Kriangsak Pimda, Arjen M. Dondorp, Nicholas J. White, Tom Van Der Poll
Published 2018

Differential expression of interferon-γ and interferon-γ- inducing cytokines in Thai patients with scrub typhus or leptospirosis

by Wirongrong Chierakul, Maaike De Fost, Yupin Suputtamongkol, Roongreung Limpaiboon, Arjen Dondorp, Nicholas J. White, Tom Van Der Poll
Published 2018

Understanding heterogeneity in biologic phenotypes of acute respiratory distress syndrome by leukocyte expression profiles

by Lieuwe D.J. Bos, Brendon P. Scicluna, David S.Y. Ong, Olaf Cremer, Tom Van Der Poll, Marcus J. Schultz
Published 2020

Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis

by W. Joost Wiersinga, Cees Van 'T Veer, Catharina W. Wieland, Sebastien Gibot, Berend Hooibrink, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
Published 2018

Immunosuppression associated with interleukin-1R-associated-kinase-M upregulation predicts mortality in Gram-negative sepsis (melioidosis)

by Willem Joost Wiersinga, Cornelis Van T. Veer, Petra S. Van Den Pangaart, Arjen M. Dondorp, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
Published 2018

Association between delay in intensive care unit admission and the host response in patients with community-acquired pneumonia

by Liza Pereverzeva, Fabrice Uhel, Hessel Peters Sengers, Olaf L. Cremer, Marcus J. Schultz, Marc M.J. Bonten, Brendon P. Scicluna, Tom van der Poll
Published 2022

The CXC chemokines gamma interferon (IFN-γ)-inducible protein 10 and monokine induced by IFN-γ are released during severe melioidosis

by Fanny N. Lauw, Andrew J.H. Simpson, Jan M. Prins, Sander J.H. Van Deventer, Wipada Chaowagul, Nicholas J. White, Tom Van Der Poll
Published 2018

Endogenous α<inf>2</inf>-antiplasmin is protective during severe gram-negative sepsis (Melioidosis)

by Liesbeth M. Kager, Tassili A. Weehuizen, W. Joost Wiersinga, Joris J.T.H. Roelofs, Joost C.M. Meijers, Arjen M. Dondorp, Cornelis Van't Veer, Tom Van Der Poll
Published 2018

Mortality and host response aberrations associated with transient and persistent acute kidney injury in critically ill patients with sepsis: a prospective cohort study

by Fabrice Uhel, Hessel Peters-Sengers, Fahimeh Falahi, Brendon P. Scicluna, Lonneke A. van Vught, Marc J. Bonten, Olaf L. Cremer, Marcus J. Schultz, Tom van der Poll
Published 2020

High-throughput mRNA profiling characterizes the expression of inflammatory molecules in sepsis caused by Burkholderia pseudomallei

by W. Joost Wiersinga, Mark C. Dessing, Piet A. Kager, Allen C. Cheng, Direk Limmathurotsakul, Nicholas P. Day, Arjen M. Dondorp, Tom Van Der Poll, Sharon J. Peacock
Published 2018

Intracellular expression of granzymes A, B, K and M in blood lymphocyte subsets of critically ill patients with or without sepsis

by M. Isabel García-Laorden, Arie J. Hoogendijk, Maryse A. Wiewel, Lonneke A. van Vught, Marcus J. Schultz, Niels Bovenschen, Alex F. de Vos, Tom van der Poll
Published 2022

Osteopontin impairs host defense during established gram-negative sepsis caused by Burkholderia pseudomallei(Melioidosis)

by Gerritje J.W. van der Windt, W. Joost Wiersinga, Catharina W. Wieland, Ivo C.S.I. Tjia, Nicholas P. Day, Sharon J. Peacock, Sandrine Florquin, Tom van der Poll
Published 2018

Diabetes does not influence activation of coagulation, fibrinolysis or anticoagulant pathways in Gram-negative sepsis (melioidosis)

by Gavin C.K.W. Koh, Joost C.M. Meijers, Rapeephan R. Maude, Direk Limmathurotsakul, Nicholas P.J. Day, Sharon J. Peacock, Tom van der Poll, Willem J. Wiersinga
Published 2018

Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis

by W. Joost Wiersinga, Catharina W. Wieland, Gerritje J.W. Van Der Windt, Anita De Boer, Sandrine Florquin, Arjen Dondorp, Nicholas P. Day, Sharon J. Peacock, Tom Van Der Poll
Published 2018

Soluble granzymes are released during human endotoxemia and in patients with severe infection due to gram-negative bacteria

by Fanny N. Lauw, Andrew J.H. Simpson, C. Erik Hack, Jan M. Prins, Angela M. Wolbink, Sander J.H. Van Deventer, Wipada Chaowagul, Nicholas J. White, Tom Van Der Poll
Published 2018

The circulatory small non-coding RNA landscape in community-acquired pneumonia on intensive care unit admission

by Hina N. Khan, Aldo Jongejan, Lonneke A. van Vught, Janneke Horn, Marcus J. Schultz, Aeilko H. Zwinderman, Olaf L. Cremer, Marc J. Bonten, Tom van der Poll, Brendon P. Scicluna
Published 2022

Elevated plasma concentrations of interferon (IFN)-γ and the IFN-γ- inducing cytokines interleukin (IL)-18, IL-12, and IL-15 in severe melioidosis

by Fanny N. Lauw, Andrew J.H. Simpson, Jan M. Prins, Michael D. Smith, Masashi Kurimoto, Sander J.H. Van Deventer, Peter Speelman, Wipada Chaowagul, Nicholas J. White, Tom Van Der Poll
Published 2018