Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia

by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y, Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah Leong, Arumugam, Thiruma
Published 2022

Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia

by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.
Published 2022

Pathophysiology of blood brain barrier dysfunction during chronic cerebral hypoperfusion in vascular cognitive impairment

by Rajeev, Vismitha, Fann, David Y, Quynh, Nhu Dinh, Kim, Hyun Ah, De Silva, T Michael, Lai, Mitchell KP, Chen, Christopher Li-Hsian, Drummond, Grant R, Sobey, Christopher G, Arumugam, Thiruma
Published 2022

The role of inflammasomes in vascular cognitive impairment

by Poh, Luting, Sim, Wei Liang, Jo, Dong-Gyu, Dinh, Quynh Nhu, Drummond, Grant R, Sobey, Christopher G, Chen, Christopher Li-Hsian, Lai, Mitchell KP, Fann, David Y, Arumugam, Thiruma V
Published 2022

Intermittent Fasting Attenuates Hallmark Vascular and Neuronal Pathologies in a Mouse Model of Vascular Cognitive Impairment

by Rajeev, Vismitha, Fann, David Y, Dinh, Quynh Nhu, Kim, Hyun Ah, De Silva, T Michael, Jo, Dong-Gyu, Drummond, Grant R, Sobey, Christopher G, Lai, Mitchell KP, Chen, Christopher Li-Hsian, V. Arumugam, Thiruma
Published 2023

Age-related eye diseases in individuals with mild cognitive impairment and Alzheimer's disease

by Chua, Jacqueline, Zhang, Zheting, Wong, Damon, Tan, Bingyao, Kulantayan, Bhavani, Sng, Chelvin C. A., Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Cheung, Carol Y., Garhöfer, Gerhard, Popa-Cherecheanu, Alina, Wong, Tien Yin, Chen, Christopher Li-Hsian, Schmetterer, Leopold
Published 2022

Longitudinal associations between β-amyloid and cortical thickness in mild cognitive impairment

by Mak, Elijah, Zhang, Liwen, Tan, Chin Hong, Reilhac, Anthonin, Shim, Hee Youn, Wen, Marcus Ong Qin, Wong, Zi Xuen, Chong, Eddie Jun Yi, Xu, Xin, Stephenson, Mary, Venketasubramanian, Narayanaswamy, Zhou, Juan Helen, O'Brien, John T., Chen, Christopher Li-Hsian
Published 2023

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y, Poh, Luting, Jo, Dong-Gyu, Herr, Deron R, Zhang, Shenpeng R, Kim, Hyun Ah, De Silva, Michael, Lai, Mitchell KP, Chen, Christopher Li-Hsian, Drummond, Grant R, Lim, Kah-Leong, Sobey, Christopher G, Arumugam, Thiruma
Published 2022

A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer's disease

by Chua, Jacqueline, Li, Chi, Ho, Lucius Kang Hua, Wong, Damon, Tan, Bingyao, Yao, Xinwen, Gan, Alfred, Schwarzhans, Florian, Garhoefer, Gerhard, Sng, Chelvin CA, Hilal, Saima, Venketasubramanian, Narayanaswamy, Cheung, Carol Y, Fischer, Georg, Vass, Clemens, Wong, Tien Yin, Chen, Christopher Li-Hsian, Schmetterer, Leopold
Published 2022

Hippocampal transcriptome profiling reveals common disease pathways in chronic hypoperfusion and aging

by Baik, Sang-Ha, Selvaraji, Sharmelee, Fann, David Y., Poh, Luting, Jo, Dong-Gyu, Herr, Deron R., Zhang, Shenpeng R., Kim, Hyun Ah, Silva, Michael De, Lai, Mitchell K. P., Chen, Christopher Li- Hsian, Drummond, Grant R., Lim, Kah-Leong, Sobey, Christopher G., Arumugam, Thiruma V.
Published 2021

A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer's disease

by Chua, Jacqueline, Li, Chi, Ho, Lucius Kang Hua, Wong, Damon, Tan, Bingyao, Yao, Xinwen, Gan, Alfred, Schwarzhans, Florian, Garhöfer, Gerhard, Sng, Chelvin C. A., Hilal, Saima, Venketasubramanian, Narayanaswamy, Cheung, Carol Y., Fischer, Georg, Vass, Clemens, Wong, Tien Yin, Chen, Christopher Li-Hsian, Schmetterer, Leopold
Published 2022

High burden of cerebral white matter lesion in 9 Asian cities

by Lam, Bonnie Yin Ka, Yiu, Brian, Ampil, Encarnita, Chen, Christopher Li-Hsian, Dikot, Yustiani, Dominguez, Jacqueline C, Ganeshbhai, Patel Vishal, Hilal, Saima, Kandiah, Nagaendran, Kim, SangYun, Lee, Jun-Young, Ong, Anam Paulus, Senanarong, Vorapun, Leung, Kam Tat, Wang, Huali, Yang, Yuan-Han, Yong, Tingting, Arshad, Faheem, Alladi, Suvarna, Wong, Samuel, Ko, Ho, Lau, Alexander Yuk Lun, Mok, Vincent Chung Tong
Published 2022