A Machine Learning Approach for Early Diagnosis of Cognitive Impairment Using Population-Based Data

by Tan, Wei Ying, Hargreaves, Carol, Chen, Christopher, Hilal, Saima
Published 2023

Factors Associated with RANTES, EMMPIRIN, MMP2 and MMP9, and the Association of These Biomarkers with Cardiovascular Disease in a Multi-Ethnic Population

by Wang, Laureen Yi-Ting, Tan, Chuen Seng, Lai, Mitchell KP, Hilal, Saima
Published 2023

Retinal parameters, cortical cerebral microinfarcts, and their interaction with cognitive impairment

by Hilal, Saima, Cheung, Carol Y, Wong, Tien Yin, Schmetterer, Leopold, Chen, Christopher
Published 2022

Comorbid cerebrovascular and neurodegenerative burden in mild behavioral impairment and their impact on clinical trajectory

by Kan, Cheuk Ni, Hilal, Saima, Xu, Xin, Venketasubramanian, Narayanaswamy, Chen, Christopher, Tan, Chin Hong
Published 2025

MRI Markers of Mixed Pathology and Cognitive Impairment in Multiethnic Asians

by Tan, Chin Hong, Hilal, Saima, Xu, Xin, Vrooman, Henri, Cheng, Ching-Yu, Wong, Tien Yin, Venketasubramanian, Narayanaswamy, Chen, Christopher
Published 2020

Improved amyloid burden quantification with nonspecific estimates using deep learning

by Liu, Haohui, Nai, Ying-Hwey, Saridin, Francis, Tanaka, Tomotaka, O' Doherty, Jim, Hilal, Saima, Gyanwali, Bibek, Chen, Christopher P, Robins, Edward G, Reilhac, Anthonin
Published 2022

The role of perfusion, grey matter volume and behavioural phenotypes in the data-driven classification of cognitive syndromes

by Vipin, Ashwati, Lee, Bernett Teck Kwong, Kumar, Dilip, Soo, See Ann, Leow, Yi Jin, Ghildiyal, Smriti, Lee, Faith Phemie Hui En, Hilal, Saima, Kandiah, Nagaendran
Published 2024

Chronic cerebral hypoperfusion alters the CypA-EMMPRIN-gelatinase pathway: Implications for vascular dementia

by Chai, Yuek Ling, Rajeev, Vismitha, Poh, Luting, Selvaraji, Sharmelee, Hilal, Saima, Chen, Christopher P, Jo, Dong-Gyu, Koo, Edward H, Arumugam, Thiruma, Lai, Mitchell KP
Published 2023

Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia

by Wu, Liu-Yun, Cheah, Irwin K, Chong, Joyce Ruifen, Chai, Yuek Ling, Tan, Jia Yun, Hilal, Saima, Vrooman, Henri, Chen, Christopher P, Halliwell, Barry, Lai, Mitchell KP
Published 2022

Effects of Carotid Artery Stiffness on Cerebral Small-Vessel Disease and Cognition

by Robert, Caroline, Ling, Lieng-Hsi, Tan, Eugene SJ, Gyanwali, Bibek, Venketasubramanian, Narayanaswamy, Lim, Shir Lynn, Gong, Lingli, Berboso, Josephine Lunaria, Richards, Arthur Mark, Chen, Christopher, Hilal, Saima
Published 2023

Elevated Soluble TNF-Receptor 1 in the Serum of Predementia Subjects with Cerebral Small Vessel Disease

by Salai, Kaung HT, Wu, Liu-Yun, Chong, Joyce RR, Chai, Yuek Ling, Gyanwali, Bibek, Robert, Caroline, Hilal, Saima, Venketasubramanian, Narayanaswamy, Dawe, Gavin S, Chen, Christopher PP, Lai, Mitchell KP
Published 2023

Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics

by Wu, Liu-Yun, Kan, Cheuk Ni, Cheah, Irwin K, Chong, Joyce Ruifen, Xu, Xin, Vrooman, Henri, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Halliwell, Barry, Lai, Mitchell KP
Published 2023

Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairment

by Chai, Yuek Ling, Chong, Joyce R, Raquib, Ainiah R, Xu, Xin, Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Kumar, Alan P, Sethi, Gautam, Chen, Christopher P, Lai, Mitchell KP
Published 2021

Growth differentiation factor-15 and white matter hyperintensities in cognitive impairment and dementia

by Chai, Yuek Ling, Hilal, Saima, Chong, Jenny PC, Ng, Yan Xia, Liew, Oi Wah, Xu, Xin, Ikram, Mohammad Kamran, Venketasubramanian, Narayanaswamy, Richards, A Mark, Lai, Mitchell KP, Chen, Christopher P
Published 2021

Intracranial stenosis, cerebrovascular diseases, and cognitive impairment in Chinese

by Hilal, Saima, Saini, Monica H., Tan, Chuen Seng, Dong, Yanhong, Holandez, Rachelle Layda, Niessen W.J., Vrooman, Henri A., Ting, Eric, Wong, Tien Yin, Chen, Christopher, Venketasubramanian, Narayanaswam, Ikram, Mohammad Kamran Amran
Published 2016

Plasma P‐tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular di...

by Chong, Joyce R, Ashton, Nicholas J, Karikari, Thomas K, Tanaka, Tomotaka, Saridin, Francis N, Reilhac, Anthonin, Robins, Edward G, Nai, Ying-Hwey, Vrooman, Henri, Hilal, Saima, Zetterberg, Henrik, Blennow, Kaj, Lai, Mitchell KP, Chen, Christopher P
Published 2021

Age-related eye diseases in individuals with mild cognitive impairment and Alzheimer's disease

by Chua, Jacqueline, Zhang, Zheting, Wong, Damon, Tan, Bingyao, Kulantayan, Bhavani, Sng, Chelvin C. A., Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Cheung, Carol Y., Garhöfer, Gerhard, Popa-Cherecheanu, Alina, Wong, Tien Yin, Chen, Christopher Li-Hsian, Schmetterer, Leopold
Published 2022

Diffusion MRI harmonization enables joint-analysis of multicentre data of patients with cerebral small vessel disease

by Robalo, Bruno M de Brito, Biessels, Geert Jan, Chen, Christopher, Dewenter, Anna, Duering, Marco, Hilal, Saima, Koek, Huiberdina L, Kopczak, Anna, Lam, Bonnie Yin Ka, Leemans, Alexander, Mok, Vincent, Onkenhout, Laurien P, van den Brink, Hilde, de Luca, Alberto
Published 2022

Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer's disease and vascular cognitive impairment

by Chua, Xin Ying, Chai, Yuek Ling, Chew, Wee Siong, Chong, Joyce R, Ang, Hui Li, Xiang, Ping, Camara, Kaddy, Howell, Amy R, Torta, Federico, Wenk, Markus R, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Herr, Deron R, Lai, Mitchell KP
Published 2021

A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer's disease

by Chua, Jacqueline, Li, Chi, Ho, Lucius Kang Hua, Wong, Damon, Tan, Bingyao, Yao, Xinwen, Gan, Alfred, Schwarzhans, Florian, Garhoefer, Gerhard, Sng, Chelvin CA, Hilal, Saima, Venketasubramanian, Narayanaswamy, Cheung, Carol Y, Fischer, Georg, Vass, Clemens, Wong, Tien Yin, Chen, Christopher Li-Hsian, Schmetterer, Leopold
Published 2022