VASCULAR AND INFLAMMATORY BLOOD BIOMARKERS OF COGNITIVE IMPAIRMENT AND DEMENTIA

by CHAI YUEK LING
Published 2020

Autoantibodies to GM1 and GQ1b alpha are not Biological Markers of Alzheimer's Disease

by Miura, Yumako, Miyaji, Kazuki, Chai, Yuek Ling, Chen, Christopher LH, Lai, Mitchell KP, Yuki, Nobuhiro
Published 2021

Mitochondrial Translocase of the Outer Membrane Alterations May Underlie Dysfunctional Oxidative Phosphorylation in Alzheimer's Disease

by Chai, Yuek Ling, Xing, Huayang, Chong, Joyce R, Francis, Paul T, Ballard, Clive G, Chen, Christopher P, Lai, Mitchell KP
Published 2021

An iTRAQ-based proteomic analysis reveals dysregulation of neocortical synaptopodin in Lewy body dementias

by Datta, Arnab, Chai, Yuek Ling, Tan, Jing Min, Lee, Jasinda H., Francis, Paul T., Chen, Christopher P., Sze, Siu Kwan, Lai, Mitchell K. P.
Published 2018

Chronic cerebral hypoperfusion alters the CypA-EMMPRIN-gelatinase pathway: Implications for vascular dementia

by Chai, Yuek Ling, Rajeev, Vismitha, Poh, Luting, Selvaraji, Sharmelee, Hilal, Saima, Chen, Christopher P, Jo, Dong-Gyu, Koo, Edward H, Arumugam, Thiruma, Lai, Mitchell KP
Published 2023

Lysosomal cathepsin D is upregulated in Alzheimer's disease neocortex and may be a marker for neurofibrillary degeneration

by Chai, Yuek Ling, Chong, Joyce R, Weng, Jiaju, Howlett, David, Halsey, Andrea, Lee, Jasinda H, Attems, Johannes, Aarsland, Dag, Francis, Paul T, Chet, Christopher P, Lai, Mitchell K
Published 2021

Inflammatory panel cytokines are elevated in the neocortex of late-stage Alzheimer's disease but not Lewy body dementias.

by Chai, Yuek Ling, Lee, Jasinda H, Chong, Joyce R, Ballard, Clive, Francis, Paul T, Kennedy, Brian K, Arumugam, Thiruma V, Chen, Christopher P, Aarsland, Dag, Lai, Mitchell KP
Published 2023

Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia

by Wu, Liu-Yun, Cheah, Irwin K, Chong, Joyce Ruifen, Chai, Yuek Ling, Tan, Jia Yun, Hilal, Saima, Vrooman, Henri, Chen, Christopher P, Halliwell, Barry, Lai, Mitchell KP
Published 2022

Elevated Soluble TNF-Receptor 1 in the Serum of Predementia Subjects with Cerebral Small Vessel Disease

by Salai, Kaung HT, Wu, Liu-Yun, Chong, Joyce RR, Chai, Yuek Ling, Gyanwali, Bibek, Robert, Caroline, Hilal, Saima, Venketasubramanian, Narayanaswamy, Dawe, Gavin S, Chen, Christopher PP, Lai, Mitchell KP
Published 2023

Plasma osteopontin as a biomarker of Alzheimer's disease and vascular cognitive impairment

by Chai, Yuek Ling, Chong, Joyce R, Raquib, Ainiah R, Xu, Xin, Hilal, Saima, Venketasubramanian, Narayanaswamy, Tan, Boon Yeow, Kumar, Alan P, Sethi, Gautam, Chen, Christopher P, Lai, Mitchell KP
Published 2021

Growth differentiation factor-15 and white matter hyperintensities in cognitive impairment and dementia

by Chai, Yuek Ling, Hilal, Saima, Chong, Jenny PC, Ng, Yan Xia, Liew, Oi Wah, Xu, Xin, Ikram, Mohammad Kamran, Venketasubramanian, Narayanaswamy, Richards, A Mark, Lai, Mitchell KP, Chen, Christopher P
Published 2021

Immunomodulatory sphingosine-1-phosphates as plasma biomarkers of Alzheimer's disease and vascular cognitive impairment

by Chua, Xin Ying, Chai, Yuek Ling, Chew, Wee Siong, Chong, Joyce R, Ang, Hui Li, Xiang, Ping, Camara, Kaddy, Howell, Amy R, Torta, Federico, Wenk, Markus R, Hilal, Saima, Venketasubramanian, Narayanaswamy, Chen, Christopher P, Herr, Deron R, Lai, Mitchell KP
Published 2021